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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASTL All Species: 4.55
Human Site: S359 Identified Species: 14.29
UniProt: Q6HA08 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6HA08 NP_001002036.3 431 45964 S359 K K L S A E A S A R Q P Q T L
Chimpanzee Pan troglodytes XP_001144288 431 45537 S359 K K L S A E A S A R Q P Q T L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540167 517 55710 A349 L R E V G G E A S A G L L Q I
Cat Felis silvestris
Mouse Mus musculus Q6HA09 435 47436 L359 S T F S V G A L A R P P Q M L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P42664 514 56826 C363 P V L V N R A C G T G L I P L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres NP_001072106 262 29919 D193 N W E N I Y S D M A Y N F Y L
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19269 503 56893 E415 R K A C N L C E V E V T T T T
Sea Urchin Strong. purpuratus P98069 639 71875 M510 I K S T G N K M M V T F V S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 N.A. 58.7 N.A. 67.3 N.A. N.A. N.A. N.A. 26.4 N.A. 22.9 N.A. N.A. 26.8 24.4
Protein Similarity: 100 96.9 N.A. 66.5 N.A. 74.9 N.A. N.A. N.A. N.A. 41.4 N.A. 36.8 N.A. N.A. 42.1 35.6
P-Site Identity: 100 100 N.A. 0 N.A. 46.6 N.A. N.A. N.A. N.A. 20 N.A. 6.6 N.A. N.A. 13.3 6.6
P-Site Similarity: 100 100 N.A. 26.6 N.A. 46.6 N.A. N.A. N.A. N.A. 20 N.A. 20 N.A. N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 25 0 50 13 38 25 0 0 0 0 0 % A
% Cys: 0 0 0 13 0 0 13 13 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 13 % D
% Glu: 0 0 25 0 0 25 13 13 0 13 0 0 0 0 0 % E
% Phe: 0 0 13 0 0 0 0 0 0 0 0 13 13 0 0 % F
% Gly: 0 0 0 0 25 25 0 0 13 0 25 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 0 0 0 13 0 0 0 0 0 0 0 13 0 13 % I
% Lys: 25 50 0 0 0 0 13 0 0 0 0 0 0 0 0 % K
% Leu: 13 0 38 0 0 13 0 13 0 0 0 25 13 0 63 % L
% Met: 0 0 0 0 0 0 0 13 25 0 0 0 0 13 0 % M
% Asn: 13 0 0 13 25 13 0 0 0 0 0 13 0 0 0 % N
% Pro: 13 0 0 0 0 0 0 0 0 0 13 38 0 13 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 25 0 38 13 0 % Q
% Arg: 13 13 0 0 0 13 0 0 0 38 0 0 0 0 0 % R
% Ser: 13 0 13 38 0 0 13 25 13 0 0 0 0 13 0 % S
% Thr: 0 13 0 13 0 0 0 0 0 13 13 13 13 38 13 % T
% Val: 0 13 0 25 13 0 0 0 13 13 13 0 13 0 0 % V
% Trp: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 0 0 0 13 0 0 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _