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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC7
All Species:
36.06
Human Site:
S91
Identified Species:
66.11
UniProt:
Q6I9Y2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6I9Y2
NP_079351.2
204
23743
S91
I
Y
K
E
I
E
C
S
I
A
G
A
H
E
K
Chimpanzee
Pan troglodytes
XP_528705
469
52055
S356
I
Y
K
E
I
E
C
S
I
A
G
A
H
E
K
Rhesus Macaque
Macaca mulatta
XP_001090043
359
40559
S246
I
Y
K
E
I
E
C
S
I
A
G
A
H
E
K
Dog
Lupus familis
XP_533771
234
27332
S121
I
Y
K
E
I
E
C
S
I
A
G
A
H
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMY4
204
23696
S91
I
Y
K
E
I
E
C
S
I
A
G
A
H
E
K
Rat
Rattus norvegicus
XP_001069423
224
26182
S111
I
Y
K
E
I
E
C
S
I
A
G
A
H
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515143
158
18762
Q62
E
C
K
K
Q
I
L
Q
A
K
R
I
R
K
N
Chicken
Gallus gallus
NP_001091708
204
23854
S91
I
Y
K
D
I
E
N
S
I
A
A
A
H
E
K
Frog
Xenopus laevis
Q7SZ78
201
23353
S91
I
Y
V
D
I
E
S
S
I
A
A
A
H
E
K
Zebra Danio
Brachydanio rerio
Q6DGZ3
202
23624
S92
I
Y
T
D
I
E
K
S
I
A
S
A
H
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRJ8
288
33033
S107
L
V
E
H
H
E
E
S
I
V
L
A
K
A
E
Honey Bee
Apis mellifera
XP_001121054
204
23930
Q86
L
S
K
E
I
E
I
Q
I
E
E
A
K
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791518
208
24366
N90
L
Y
S
T
I
E
H
N
I
K
D
A
H
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.5
56.5
84.1
N.A.
97.5
87.5
N.A.
71.5
92.6
86.7
75.9
N.A.
30.2
51.4
N.A.
52.4
Protein Similarity:
100
43.5
56.8
86.7
N.A.
99.5
89.7
N.A.
75.9
96
93.1
89.2
N.A.
45.8
69.1
N.A.
71.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
80
73.3
73.3
N.A.
26.6
40
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
86.6
80
80
N.A.
46.6
53.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
70
16
93
0
8
0
% A
% Cys:
0
8
0
0
0
0
47
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
0
0
0
0
0
0
8
0
0
0
8
% D
% Glu:
8
0
8
54
0
93
8
0
0
8
8
0
0
70
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% G
% His:
0
0
0
8
8
0
8
0
0
0
0
0
77
0
0
% H
% Ile:
70
0
0
0
85
8
8
0
93
0
0
8
0
0
0
% I
% Lys:
0
0
70
8
0
0
8
0
0
16
0
0
16
16
70
% K
% Leu:
24
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
16
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% R
% Ser:
0
8
8
0
0
0
8
77
0
0
8
0
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
8
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _