KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS7B
All Species:
28.18
Human Site:
T106
Identified Species:
47.69
UniProt:
Q6IAN0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IAN0
NP_056325.2
325
35119
T106
S
H
A
T
K
V
Q
T
H
K
P
Y
L
V
T
Chimpanzee
Pan troglodytes
XP_511344
325
35116
T106
S
H
A
T
K
V
Q
T
H
K
P
Y
L
V
T
Rhesus Macaque
Macaca mulatta
XP_001103593
371
40181
T152
S
H
A
T
K
V
Q
T
H
K
P
Y
L
V
T
Dog
Lupus familis
XP_536670
325
35359
T106
S
P
A
T
K
V
Q
T
H
K
P
Y
M
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99J47
323
34968
T104
A
G
S
S
Q
G
Q
T
H
Q
P
F
V
V
T
Rat
Rattus norvegicus
Q5RJY4
325
35324
T106
S
S
S
S
Q
G
Q
T
H
Q
P
C
V
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511308
544
58832
T325
T
T
N
Q
P
K
K
T
H
K
P
H
I
V
T
Chicken
Gallus gallus
Q6PUF4
287
31460
G82
M
K
K
C
L
T
L
G
A
K
K
V
F
Y
I
Frog
Xenopus laevis
Q0IH28
323
35135
L90
M
R
L
K
S
T
Q
L
H
K
P
H
M
V
I
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
T91
K
T
Y
G
K
T
K
T
Y
T
P
C
T
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
A105
L
A
L
D
V
D
P
A
Y
P
P
T
V
L
P
Honey Bee
Apis mellifera
XP_394428
317
36148
T100
N
T
H
V
T
V
P
T
Y
P
P
V
V
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793326
411
43892
A193
G
P
E
I
G
I
P
A
H
T
P
H
V
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
D61
E
E
L
K
K
T
I
D
Q
E
F
P
N
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
84.9
87
N.A.
77.5
77.5
N.A.
46.3
24.9
63.6
54.7
N.A.
43.2
45.2
N.A.
37.7
Protein Similarity:
100
99.3
86.7
93.2
N.A.
88.3
88
N.A.
54
46.1
78.1
74.4
N.A.
61.6
63.3
N.A.
53.7
P-Site Identity:
100
100
100
86.6
N.A.
40
46.6
N.A.
40
6.6
33.3
33.3
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
66.6
6.6
46.6
46.6
N.A.
26.6
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
29
0
0
0
0
15
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
8
8
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
8
0
0
% F
% Gly:
8
8
0
8
8
15
0
8
0
0
0
0
0
0
0
% G
% His:
0
22
8
0
0
0
0
0
65
0
0
22
0
0
0
% H
% Ile:
0
0
0
8
0
8
8
0
0
0
0
0
8
8
15
% I
% Lys:
8
8
8
15
43
8
15
0
0
50
8
0
0
0
8
% K
% Leu:
8
0
22
0
8
0
8
8
0
0
0
0
22
15
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
15
0
0
8
0
22
0
0
15
86
8
0
0
22
% P
% Gln:
0
0
0
8
15
0
50
0
8
15
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
36
8
15
15
8
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
22
0
29
8
29
0
65
0
15
0
8
8
0
58
% T
% Val:
0
0
0
8
8
36
0
0
0
0
0
15
36
65
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
22
0
0
29
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _