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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWF2
All Species:
27.58
Human Site:
S277
Identified Species:
55.15
UniProt:
Q6IBS0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IBS0
NP_009215.1
349
39548
S277
M
L
Y
S
S
C
K
S
R
L
L
D
S
V
E
Chimpanzee
Pan troglodytes
XP_001171340
1325
149159
S277
M
L
Y
S
S
C
K
S
R
L
L
D
S
V
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859685
349
39451
S277
M
L
Y
S
S
C
K
S
R
L
L
D
S
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0P5
349
39452
S277
M
L
Y
S
S
C
K
S
R
L
L
D
S
V
E
Rat
Rattus norvegicus
Q5RJR2
350
40072
S277
M
L
Y
S
S
C
K
S
P
L
L
D
I
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510564
313
35921
T269
I
G
D
G
A
E
L
T
A
D
F
L
Y
D
E
Chicken
Gallus gallus
Q5ZM35
349
39817
S277
M
L
Y
S
S
C
K
S
R
L
L
D
T
V
E
Frog
Xenopus laevis
Q7ZXP0
349
39859
N277
M
L
Y
S
S
C
K
N
R
L
L
D
S
V
E
Zebra Danio
Brachydanio rerio
Q6GMH3
347
39840
S275
M
L
Y
S
S
C
K
S
R
L
L
D
E
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFM9
343
39052
A277
M
M
Y
S
S
C
K
A
P
F
L
D
E
L
A
Honey Bee
Apis mellifera
XP_393653
350
39782
A278
M
L
Y
S
S
C
K
A
P
L
L
E
L
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53250
332
37052
Q274
I
N
Y
L
K
N
D
Q
K
I
A
F
S
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26
N.A.
96.2
N.A.
96.5
64.8
N.A.
76.5
83.9
79.6
71.9
N.A.
49.2
51.7
N.A.
N.A.
Protein Similarity:
100
26.2
N.A.
97.7
N.A.
98.8
84.5
N.A.
84.2
93.4
91.6
85.3
N.A.
67.6
72.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
86.6
N.A.
6.6
93.3
93.3
93.3
N.A.
53.3
60
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
86.6
N.A.
26.6
100
100
93.3
N.A.
73.3
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
17
9
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
9
0
0
9
0
75
0
9
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
9
17
0
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
9
9
0
0
0
% F
% Gly:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% I
% Lys:
0
0
0
0
9
0
84
0
9
0
0
0
0
9
0
% K
% Leu:
0
75
0
9
0
0
9
0
0
75
84
9
9
9
0
% L
% Met:
84
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% R
% Ser:
0
0
0
84
84
0
0
59
0
0
0
0
50
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
92
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _