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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWF2
All Species:
38.18
Human Site:
T148
Identified Species:
76.36
UniProt:
Q6IBS0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IBS0
NP_009215.1
349
39548
T148
C
A
A
P
A
P
L
T
S
A
E
R
E
L
Q
Chimpanzee
Pan troglodytes
XP_001171340
1325
149159
T148
C
A
A
P
A
P
L
T
S
A
E
R
E
L
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859685
349
39451
T148
C
A
A
P
A
P
L
T
S
A
E
R
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0P5
349
39452
T148
C
A
A
P
A
P
L
T
S
A
E
R
E
L
Q
Rat
Rattus norvegicus
Q5RJR2
350
40072
T148
Q
S
S
P
A
P
L
T
A
A
E
E
E
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510564
313
35921
E150
L
A
F
P
L
Q
P
E
A
Q
Q
A
I
Q
L
Chicken
Gallus gallus
Q5ZM35
349
39817
T148
C
S
A
P
A
P
L
T
A
A
E
Q
E
L
Q
Frog
Xenopus laevis
Q7ZXP0
349
39859
T148
C
A
A
P
A
P
L
T
A
A
E
R
E
L
Q
Zebra Danio
Brachydanio rerio
Q6GMH3
347
39840
T146
C
S
A
P
A
P
L
T
V
A
E
Q
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFM9
343
39052
T148
F
A
A
P
A
P
L
T
S
R
E
E
E
L
K
Honey Bee
Apis mellifera
XP_393653
350
39782
T149
N
A
A
P
A
P
L
T
T
A
E
E
E
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53250
332
37052
L156
E
I
N
K
Q
Q
A
L
L
R
K
N
T
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26
N.A.
96.2
N.A.
96.5
64.8
N.A.
76.5
83.9
79.6
71.9
N.A.
49.2
51.7
N.A.
N.A.
Protein Similarity:
100
26.2
N.A.
97.7
N.A.
98.8
84.5
N.A.
84.2
93.4
91.6
85.3
N.A.
67.6
72.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
60
N.A.
13.3
80
93.3
80
N.A.
73.3
73.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
86.6
N.A.
26.6
100
100
93.3
N.A.
80
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
75
0
84
0
9
0
34
75
0
9
0
0
9
% A
% Cys:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
9
0
0
84
25
84
0
0
% E
% Phe:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% K
% Leu:
9
0
0
0
9
0
84
9
9
0
0
0
0
84
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
92
0
84
9
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
9
17
0
0
0
9
9
17
0
9
59
% Q
% Arg:
0
0
0
0
0
0
0
0
0
17
0
42
0
0
9
% R
% Ser:
0
25
9
0
0
0
0
0
42
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
84
9
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _