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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCAPH2 All Species: 21.52
Human Site: S581 Identified Species: 39.44
UniProt: Q6IBW4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IBW4 NP_055366.3 605 68227 S581 E M A V D T M S L R L L T H Q
Chimpanzee Pan troglodytes XP_001142278 606 68190 S582 E M A V D T M S L R L L T H Q
Rhesus Macaque Macaca mulatta XP_001112760 611 68740 S587 E T A V D T M S L R L L T H Q
Dog Lupus familis XP_531688 603 68122 S579 E A A V D T M S L R L L T H Q
Cat Felis silvestris
Mouse Mus musculus Q8BSP2 607 68927 S583 E A A V D T M S L R L L T H Q
Rat Rattus norvegicus Q4V8I2 554 62619 S530 E A A V D T M S L R L L T H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520395 176 19702 L153 E G V D T M A L R L L S R Q R
Chicken Gallus gallus XP_423939 612 68715 R589 E E A V D T V R L R L L T R E
Frog Xenopus laevis Q641G4 624 71178 A600 H E G L D T M A L R L L S Q Q
Zebra Danio Brachydanio rerio Q5RH01 592 67008 E567 D C S V D T M E L T L L T T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789356 666 75185 A640 D E G M D T M A L K L L N M K
Poplar Tree Populus trichocarpa XP_002328598 645 72418 N581 Y S A V N P F N V R L L G H K
Maize Zea mays NP_001144836 657 72430 A568 N E L V C Y T A E N P F H V R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 94.1 81.4 N.A. 80.5 72.7 N.A. 21.9 55 51.7 40.9 N.A. N.A. N.A. N.A. 21.6
Protein Similarity: 100 99.1 96.2 87.4 N.A. 86.6 78.6 N.A. 24.6 67.3 66.3 59.8 N.A. N.A. N.A. N.A. 40
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 13.3 66.6 53.3 60 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 20 80 73.3 73.3 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: 22.9 21.6 N.A. N.A. N.A. N.A.
Protein Similarity: 42 39.4 N.A. N.A. N.A. N.A.
P-Site Identity: 40 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 66.6 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 62 0 0 0 8 24 0 0 0 0 0 0 0 % A
% Cys: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 8 77 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 62 31 0 0 0 0 0 8 8 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 16 0 0 0 0 0 0 0 0 0 8 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 8 54 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 16 % K
% Leu: 0 0 8 8 0 0 0 8 77 8 93 85 0 0 0 % L
% Met: 0 16 0 8 0 8 70 0 0 0 0 0 0 8 0 % M
% Asn: 8 0 0 0 8 0 0 8 0 8 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 62 % Q
% Arg: 0 0 0 0 0 0 0 8 8 70 0 0 8 8 16 % R
% Ser: 0 8 8 0 0 0 0 47 0 0 0 8 8 0 0 % S
% Thr: 0 8 0 0 8 77 8 0 0 8 0 0 62 8 0 % T
% Val: 0 0 8 77 0 0 8 0 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _