KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRAMD4
All Species:
16.06
Human Site:
S500
Identified Species:
44.17
UniProt:
Q6IC98
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IC98
NP_055939.1
578
66408
S500
N
Y
L
C
F
E
S
S
K
S
G
S
S
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117564
401
46647
V327
K
F
Q
L
V
L
D
V
A
Q
K
A
Q
N
L
Dog
Lupus familis
XP_538323
540
62509
R460
S
S
A
A
V
S
R
R
L
Q
T
T
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CB44
633
72245
S555
N
Y
L
C
F
E
S
S
K
S
G
S
S
K
R
Rat
Rattus norvegicus
XP_235571
606
69379
S528
N
Y
L
C
F
E
S
S
K
S
G
S
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506007
216
24310
G142
C
F
E
S
S
K
S
G
S
S
K
R
N
K
V
Chicken
Gallus gallus
Frog
Xenopus laevis
A2RV80
578
66528
S501
N
F
L
C
F
E
S
S
R
S
G
S
S
K
R
Zebra Danio
Brachydanio rerio
XP_694731
585
67264
S503
L
C
F
E
S
S
S
S
R
A
T
S
S
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023583
644
73132
R565
A
A
L
V
F
R
P
R
N
H
T
D
D
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
64.7
81.1
N.A.
86
90.2
N.A.
34
N.A.
80.2
72.3
N.A.
N.A.
N.A.
21.5
N.A.
Protein Similarity:
100
N.A.
65.2
83.2
N.A.
88.6
92.5
N.A.
35.4
N.A.
89.9
86.5
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
N.A.
0
13.3
N.A.
100
100
N.A.
20
N.A.
86.6
33.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
13.3
26.6
N.A.
100
100
N.A.
40
N.A.
100
53.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
12
0
0
0
0
12
12
0
12
0
0
0
% A
% Cys:
12
12
0
45
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
12
12
0
0
% D
% Glu:
0
0
12
12
0
45
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
34
12
0
56
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
45
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
12
0
0
34
0
23
0
0
78
12
% K
% Leu:
12
0
56
12
0
12
0
0
12
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
45
0
0
0
0
0
0
0
12
0
0
0
12
12
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
23
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
12
12
23
23
0
0
12
0
0
56
% R
% Ser:
12
12
0
12
23
23
67
56
12
56
0
56
67
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
34
12
0
0
0
% T
% Val:
0
0
0
12
23
0
0
12
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _