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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPPDE2
All Species:
24.85
Human Site:
S25
Identified Species:
45.56
UniProt:
Q6ICB0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ICB0
NP_056519.1
168
18263
S25
K
G
L
A
R
R
L
S
P
I
M
L
G
K
Q
Chimpanzee
Pan troglodytes
XP_001169693
209
22990
S25
K
G
L
A
R
R
L
S
P
I
M
L
G
K
Q
Rhesus Macaque
Macaca mulatta
XP_001105810
239
26227
S25
K
G
L
A
R
R
L
S
P
I
M
L
G
K
Q
Dog
Lupus familis
XP_852124
168
18487
S25
K
G
L
A
R
R
L
S
P
I
M
L
G
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQT7
168
18366
S25
K
G
L
A
R
R
L
S
P
I
M
L
G
K
Q
Rat
Rattus norvegicus
Q5XIT6
194
21400
G25
N
E
Y
T
S
S
I
G
I
G
V
F
H
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515258
182
19837
S39
N
L
S
V
N
L
F
S
L
L
S
P
G
K
Q
Chicken
Gallus gallus
Q5ZIV7
193
21391
E33
G
V
F
H
S
G
I
E
V
Y
G
R
E
F
A
Frog
Xenopus laevis
Q6GLM5
169
18719
S26
R
G
L
A
R
R
L
S
P
V
M
L
G
K
Q
Zebra Danio
Brachydanio rerio
Q6DC39
196
21840
I25
E
F
T
S
S
L
G
I
G
V
F
H
S
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002303035
284
30455
V70
Y
G
T
P
I
K
V
V
D
L
G
I
T
H
V
Maize
Zea mays
NP_001149830
262
28071
Y98
P
R
Y
T
A
E
T
Y
R
L
L
T
H
N
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93VG8
224
25331
W44
P
V
N
N
Y
L
Y
W
F
G
I
G
I
F
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.8
65.2
92.2
N.A.
97
22.1
N.A.
77.4
23.8
73.9
23.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.2
66.1
96.4
N.A.
98.2
39.1
N.A.
81.8
39.9
86.3
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
26.6
0
86.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
33.3
6.6
100
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.6
32.4
N.A.
21.4
N.A.
N.A.
Protein Similarity:
40.4
43.1
N.A.
33
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
13.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
47
8
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
8
0
8
0
0
0
0
8
0
0
% E
% Phe:
0
8
8
0
0
0
8
0
8
0
8
8
0
16
0
% F
% Gly:
8
54
0
0
0
8
8
8
8
16
16
8
54
8
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
16
8
8
% H
% Ile:
0
0
0
0
8
0
16
8
8
39
8
8
8
0
8
% I
% Lys:
39
0
0
0
0
8
0
0
0
0
0
0
0
54
0
% K
% Leu:
0
8
47
0
0
24
47
0
8
24
8
47
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% M
% Asn:
16
0
8
8
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
16
0
0
8
0
0
0
0
47
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% Q
% Arg:
8
8
0
0
47
47
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
0
8
8
24
8
0
54
0
0
8
0
8
8
0
% S
% Thr:
0
0
16
16
0
0
8
0
0
0
0
8
8
0
0
% T
% Val:
0
16
0
8
0
0
8
8
8
16
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
0
8
0
8
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _