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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPPDE2 All Species: 25.45
Human Site: Y12 Identified Species: 46.67
UniProt: Q6ICB0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ICB0 NP_056519.1 168 18263 Y12 N L Y P V K L Y V Y D L S K G
Chimpanzee Pan troglodytes XP_001169693 209 22990 Y12 N L Y P V K L Y V Y D L S K G
Rhesus Macaque Macaca mulatta XP_001105810 239 26227 Y12 N L Y P V K L Y V Y D L S K G
Dog Lupus familis XP_852124 168 18487 Y12 N L Y P V K L Y V Y D L S K G
Cat Felis silvestris
Mouse Mus musculus Q9CQT7 168 18366 Y12 N L Y P V K L Y V Y D L S K G
Rat Rattus norvegicus Q5XIT6 194 21400 Y12 Q L V V L N V Y D M Y W M N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515258 182 19837 P26 H L P R L L E P Q G P A L N L
Chicken Gallus gallus Q5ZIV7 193 21391 T20 M Y W M N E Y T S S L G I G V
Frog Xenopus laevis Q6GLM5 169 18719 Y13 G P H L V R L Y V Y D M S R G
Zebra Danio Brachydanio rerio Q6DC39 196 21840 D12 P V I L N V Y D M Y W I N E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002303035 284 30455 P57 G G G I Q H L P S G T T P Y G
Maize Zea mays NP_001149830 262 28071 Y85 P R E V F E D Y L R D I A P R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93VG8 224 25331 N31 A L T P V Y L N V Y D L T P V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.8 65.2 92.2 N.A. 97 22.1 N.A. 77.4 23.8 73.9 23.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73.2 66.1 96.4 N.A. 98.2 39.1 N.A. 81.8 39.9 86.3 39.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 6.6 0 53.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 20 13.3 80 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 31.6 32.4 N.A. 21.4 N.A. N.A.
Protein Similarity: 40.4 43.1 N.A. 33 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 53.3 N.A. N.A.
P-Site Similarity: 13.3 40 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 8 8 0 62 0 0 0 0 % D
% Glu: 0 0 8 0 0 16 8 0 0 0 0 0 0 8 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 16 8 8 0 0 0 0 0 0 16 0 8 0 8 54 % G
% His: 8 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 0 16 8 0 0 % I
% Lys: 0 0 0 0 0 39 0 0 0 0 0 0 0 39 0 % K
% Leu: 0 62 0 16 16 8 62 0 8 0 8 47 8 0 8 % L
% Met: 8 0 0 8 0 0 0 0 8 8 0 8 8 0 0 % M
% Asn: 39 0 0 0 16 8 0 8 0 0 0 0 8 16 0 % N
% Pro: 16 8 8 47 0 0 0 16 0 0 8 0 8 16 0 % P
% Gln: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 8 0 8 0 8 0 0 0 8 0 0 0 8 8 % R
% Ser: 0 0 0 0 0 0 0 0 16 8 0 0 47 0 0 % S
% Thr: 0 0 8 0 0 0 0 8 0 0 8 8 8 0 0 % T
% Val: 0 8 8 16 54 8 8 0 54 0 0 0 0 0 16 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 8 8 0 0 0 % W
% Tyr: 0 8 39 0 0 8 16 62 0 62 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _