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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM109B
All Species:
23.03
Human Site:
S141
Identified Species:
63.33
UniProt:
Q6ICB4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ICB4
NP_001002034.2
259
28338
S141
Q
L
Q
D
A
R
Q
S
L
A
L
Q
R
R
S
Chimpanzee
Pan troglodytes
XP_001154643
306
33025
S188
Q
L
Q
D
A
R
Q
S
L
A
L
Q
R
R
S
Rhesus Macaque
Macaca mulatta
XP_001106558
259
28383
S141
Q
L
Q
D
A
R
Q
S
L
A
L
Q
R
R
S
Dog
Lupus familis
XP_538346
257
28629
S141
Q
L
R
D
A
R
H
S
L
A
L
R
R
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q14B98
259
28689
S141
Q
L
Q
D
A
R
Q
S
L
A
L
H
R
C
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516903
244
26336
A115
W
V
K
A
L
S
R
A
S
F
G
Y
M
R
L
Chicken
Gallus gallus
XP_425472
251
28399
S140
Q
L
E
E
A
C
T
S
L
A
A
C
R
K
S
Frog
Xenopus laevis
NP_001084930
246
27986
T126
Q
L
E
L
M
Q
K
T
S
I
R
R
K
P
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395804
216
25109
L108
M
E
Q
W
M
K
A
L
A
C
A
S
Y
D
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
93.8
77.9
N.A.
78.7
N.A.
N.A.
52.5
51.3
41.7
N.A.
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
100
83.6
96.1
82.2
N.A.
86.8
N.A.
N.A.
61
58.6
52.5
N.A.
N.A.
N.A.
47.4
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
80
N.A.
N.A.
6.6
53.3
13.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
N.A.
N.A.
33.3
73.3
60
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
67
0
12
12
12
67
23
0
0
0
23
% A
% Cys:
0
0
0
0
0
12
0
0
0
12
0
12
0
12
0
% C
% Asp:
0
0
0
56
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
12
23
12
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
12
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
12
12
0
0
0
0
0
12
12
0
% K
% Leu:
0
78
0
12
12
0
0
12
67
0
56
0
0
0
12
% L
% Met:
12
0
0
0
23
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
78
0
56
0
0
12
45
0
0
0
0
34
0
0
0
% Q
% Arg:
0
0
12
0
0
56
12
0
0
0
12
23
67
45
0
% R
% Ser:
0
0
0
0
0
12
0
67
23
0
0
12
0
0
56
% S
% Thr:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _