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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C22orf25
All Species:
26.36
Human Site:
T251
Identified Species:
72.5
UniProt:
Q6ICL3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ICL3
NP_690870.3
276
30937
T251
V
D
A
D
G
H
V
T
F
T
E
R
S
M
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113606
610
67055
S251
A
M
A
L
A
A
P
S
Q
P
A
L
L
S
P
Dog
Lupus familis
XP_850154
276
30930
T251
V
D
A
D
G
H
V
T
F
T
E
R
S
M
L
Cat
Felis silvestris
Mouse
Mus musculus
P54797
276
30928
T251
V
D
A
N
G
H
V
T
F
T
E
R
S
M
L
Rat
Rattus norvegicus
NP_001101793
276
30835
T251
V
D
A
D
G
H
V
T
F
T
E
R
S
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007837
276
31134
T251
I
D
S
E
G
N
V
T
F
T
E
R
T
M
I
Frog
Xenopus laevis
NP_001083694
275
31184
T250
I
D
G
K
G
Q
V
T
F
T
E
R
T
M
L
Zebra Danio
Brachydanio rerio
NP_001003781
273
30406
S248
I
D
R
E
G
N
V
S
F
T
E
R
T
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53275
312
35667
D276
I
V
L
L
V
S
K
D
S
T
R
V
T
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
42.2
90.5
N.A.
87.3
86.9
N.A.
N.A.
73.1
68.8
64.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
44.2
94.5
N.A.
94.5
93.1
N.A.
N.A.
88
85.5
77.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
86.6
93.3
N.A.
N.A.
60
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
N.A.
100
80
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
56
0
12
12
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
78
0
34
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
23
0
0
0
0
0
0
78
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
78
0
0
0
0
12
0
% F
% Gly:
0
0
12
0
78
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
45
0
0
0
0
0
0
0
0
0
% H
% Ile:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% I
% Lys:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
23
0
0
0
0
0
0
0
12
12
0
45
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
78
12
% M
% Asn:
0
0
0
12
0
23
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
12
% Q
% Arg:
0
0
12
0
0
0
0
0
0
0
12
78
0
0
0
% R
% Ser:
0
0
12
0
0
12
0
23
12
0
0
0
45
12
0
% S
% Thr:
0
0
0
0
0
0
0
67
0
89
0
0
45
0
0
% T
% Val:
45
12
0
0
12
0
78
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _