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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C22orf25 All Species: 25.45
Human Site: Y136 Identified Species: 70
UniProt: Q6ICL3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ICL3 NP_690870.3 276 30937 Y136 A K G D V I C Y Y G N R G E P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113606 610 67055 Y136 A K G D V I C Y Y G N R G E P
Dog Lupus familis XP_850154 276 30930 Y136 E K G D V I C Y Y G N R G E P
Cat Felis silvestris
Mouse Mus musculus P54797 276 30928 Y136 S K G D V V C Y Y G N R G E P
Rat Rattus norvegicus NP_001101793 276 30835 Y136 A K G D V V C Y Y G N R G E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001007837 276 31134 Y136 T K G D V I C Y Y G N K G D P
Frog Xenopus laevis NP_001083694 275 31184 Y136 K E D V M C Y Y G S K G E Q E
Zebra Danio Brachydanio rerio NP_001003781 273 30406 Y136 N E D T L C Y Y G N K G S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53275 312 35667 S152 R T F D V L S S T C R K D L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 42.2 90.5 N.A. 87.3 86.9 N.A. N.A. 73.1 68.8 64.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 44.2 94.5 N.A. 94.5 93.1 N.A. N.A. 88 85.5 77.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 93.3 N.A. N.A. 80 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. N.A. 93.3 26.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 23 67 0 0 12 0 0 0 0 0 % C
% Asp: 0 0 23 78 0 0 0 0 0 0 0 0 12 12 12 % D
% Glu: 12 23 0 0 0 0 0 0 0 0 0 0 12 56 23 % E
% Phe: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 67 0 0 0 0 0 23 67 0 23 67 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 45 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 67 0 0 0 0 0 0 0 0 23 23 0 0 0 % K
% Leu: 0 0 0 0 12 12 0 0 0 0 0 0 0 12 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 0 0 0 12 67 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Q
% Arg: 12 0 0 0 0 0 0 0 0 0 12 56 0 0 0 % R
% Ser: 12 0 0 0 0 0 12 12 0 12 0 0 12 12 0 % S
% Thr: 12 12 0 12 0 0 0 0 12 0 0 0 0 0 0 % T
% Val: 0 0 0 12 78 23 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 23 89 67 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _