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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC35E4 All Species: 15.45
Human Site: T106 Identified Species: 37.78
UniProt: Q6ICL7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ICL7 NP_001001479.1 350 36747 T106 R R P M P G G T R C R V L L L
Chimpanzee Pan troglodytes XP_525563 350 36708 T106 R R P M P G G T R C R V L L L
Rhesus Macaque Macaca mulatta XP_001110327 350 36801 T106 R R P M P G G T R C R V L L L
Dog Lupus familis XP_543482 350 36917 T106 Q R P M P S R T R R Q V L L L
Cat Felis silvestris
Mouse Mus musculus Q8K3D6 351 37234 I106 Q R P V P H S I H R R V L L L
Rat Rattus norvegicus Q5RKL7 350 37022 I106 Q R P V P H S I H R R V L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507737 605 63812 Y359 R P P P N G L Y V V A T V A V
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017857 387 42516 A98 E Q D L T T S A K C K V F L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002311199 306 33531 S79 K T Q F L K I S A L S L V F C
Maize Zea mays NP_001152642 339 35726 Q107 S S P R S H R Q L A R V A L L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97.7 89.4 N.A. 83.4 85.4 N.A. 20.3 N.A. N.A. 46.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 98.5 92 N.A. 86 87.7 N.A. 28.2 N.A. N.A. 61.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 66.6 N.A. 53.3 53.3 N.A. 20 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 66.6 66.6 N.A. 33.3 N.A. N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 24.5 32.5 N.A. N.A. N.A. N.A.
Protein Similarity: 43.4 48.5 N.A. N.A. N.A. N.A.
P-Site Identity: 0 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 10 10 10 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 40 0 0 0 0 10 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 10 10 0 % F
% Gly: 0 0 0 0 0 40 30 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 30 0 0 20 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 20 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 10 0 0 10 0 10 0 0 0 0 % K
% Leu: 0 0 0 10 10 0 10 0 10 10 0 10 60 80 80 % L
% Met: 0 0 0 40 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 80 10 60 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 30 10 10 0 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 40 60 0 10 0 0 20 0 40 30 60 0 0 0 0 % R
% Ser: 10 10 0 0 10 10 30 10 0 0 10 0 0 0 0 % S
% Thr: 0 10 0 0 10 10 0 40 0 0 0 10 0 0 0 % T
% Val: 0 0 0 20 0 0 0 0 10 10 0 80 20 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _