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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPINK5L2
All Species:
15.15
Human Site:
Y42
Identified Species:
41.67
UniProt:
Q6IE38
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IE38
NP_001001325.1
97
11057
Y42
I
I
K
V
K
C
P
Y
E
K
V
N
L
S
W
Chimpanzee
Pan troglodytes
XP_001143620
97
11057
Y42
I
I
K
V
K
C
P
Y
E
K
V
N
L
S
W
Rhesus Macaque
Macaca mulatta
XP_001096505
97
11063
Y42
I
I
K
V
K
C
P
Y
E
K
V
N
L
S
W
Dog
Lupus familis
XP_850557
80
8676
N25
S
G
N
T
R
A
N
N
M
L
Q
R
Q
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6IE32
76
8353
D22
Y
V
C
N
C
S
V
D
C
D
I
Y
K
K
Y
Rat
Rattus norvegicus
Q6IE46
98
11219
Y43
L
I
K
I
K
C
P
Y
K
K
V
K
L
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507573
85
9126
D31
S
L
S
S
A
Q
M
D
C
S
M
Y
K
K
Y
Chicken
Gallus gallus
P01005
210
22573
S96
T
V
P
M
N
C
S
S
Y
A
N
T
T
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002660388
76
7898
S22
S
S
G
A
S
G
S
S
R
K
P
T
C
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
92.7
36
N.A.
32.9
66.3
N.A.
38.1
20.4
N.A.
34
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
95.8
47.4
N.A.
49.4
79.5
N.A.
53.6
31.4
N.A.
42.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
0
73.3
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
20
93.3
N.A.
20
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
12
0
0
0
12
0
0
0
23
0
% A
% Cys:
0
0
12
0
12
56
0
0
23
0
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
0
0
23
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
12
0
0
12
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
45
0
12
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
45
0
45
0
0
0
12
56
0
12
23
23
0
% K
% Leu:
12
12
0
0
0
0
0
0
0
12
0
0
45
0
0
% L
% Met:
0
0
0
12
0
0
12
0
12
0
12
0
0
0
0
% M
% Asn:
0
0
12
12
12
0
12
12
0
0
12
34
0
0
12
% N
% Pro:
0
0
12
0
0
0
45
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
12
0
12
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
12
0
0
12
0
0
0
% R
% Ser:
34
12
12
12
12
12
23
23
0
12
0
0
0
56
0
% S
% Thr:
12
0
0
12
0
0
0
0
0
0
0
23
12
0
0
% T
% Val:
0
23
0
34
0
0
12
0
0
0
45
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% W
% Tyr:
12
0
0
0
0
0
0
45
12
0
0
23
0
0
23
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _