KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF17
All Species:
20.3
Human Site:
T22
Identified Species:
55.83
UniProt:
Q6IE81
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IE81
NP_079176.2
842
95533
T22
D
N
G
S
L
S
T
T
W
S
Q
N
S
R
S
Chimpanzee
Pan troglodytes
XP_001158286
830
94095
T22
D
N
G
S
L
S
T
T
W
S
Q
N
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001083402
843
95661
T22
D
N
G
S
L
S
T
T
W
S
Q
N
S
R
S
Dog
Lupus familis
XP_848505
843
95658
T22
D
N
G
S
L
S
T
T
W
S
Q
N
S
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPI0
834
93879
W23
N
G
S
L
S
T
T
W
S
Q
H
S
R
S
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414632
797
89313
T22
S
D
T
T
D
S
H
T
T
S
A
S
R
C
S
Frog
Xenopus laevis
Q6GQJ2
827
94374
S22
D
N
G
S
L
S
T
S
W
S
Q
H
S
R
S
Zebra Danio
Brachydanio rerio
Q803A0
829
94529
W22
N
G
S
N
S
T
S
W
S
Q
H
S
N
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20318
1042
117625
D22
E
C
R
D
T
I
S
D
R
I
Q
Y
N
L
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.5
90.5
N.A.
92.1
N.A.
N.A.
N.A.
48.8
67.9
54.1
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
100
98.5
99.6
93.4
N.A.
95
N.A.
N.A.
N.A.
61.8
79.6
67.5
N.A.
N.A.
N.A.
39
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
N.A.
N.A.
N.A.
26.6
86.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
N.A.
N.A.
N.A.
46.6
100
40
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
56
12
0
12
12
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
23
56
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
12
0
0
0
23
12
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
0
0
12
56
0
0
0
0
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
56
0
12
0
0
0
0
0
0
0
45
23
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
23
67
0
0
0
12
% Q
% Arg:
0
0
12
0
0
0
0
0
12
0
0
0
23
56
0
% R
% Ser:
12
0
23
56
23
67
23
12
23
67
0
34
56
23
67
% S
% Thr:
0
0
12
12
12
23
67
56
12
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
23
56
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _