KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM132E
All Species:
13.03
Human Site:
T870
Identified Species:
35.83
UniProt:
Q6IEE7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IEE7
NP_997196.1
984
107094
T870
P
A
G
N
P
L
E
T
V
P
A
F
C
H
G
Chimpanzee
Pan troglodytes
XP_523601
779
84212
S676
C
C
H
G
D
H
H
S
S
G
S
S
Q
T
S
Rhesus Macaque
Macaca mulatta
XP_001113490
984
107136
T870
P
A
G
N
P
L
E
T
V
P
A
C
C
H
G
Dog
Lupus familis
XP_548267
1004
108165
T890
P
A
G
N
P
L
E
T
V
P
A
C
C
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6IEE6
982
106971
T869
P
A
G
S
A
L
E
T
V
P
A
C
C
H
G
Rat
Rattus norvegicus
Q76HP2
1097
121260
D990
E
E
Q
I
T
A
I
D
R
G
L
D
F
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508797
1090
121375
D983
D
E
Q
I
T
A
I
D
R
G
V
D
F
E
E
Chicken
Gallus gallus
XP_001234668
877
97413
Q774
G
N
P
L
E
N
V
Q
T
C
C
H
A
D
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692496
997
110906
G894
S
P
S
N
T
L
E
G
V
Q
T
C
C
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
98.4
81.3
N.A.
93.2
37.2
N.A.
39.4
71.5
N.A.
59.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77.2
98.8
84.3
N.A.
96.1
54.7
N.A.
55.5
79.9
N.A.
74.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
93.3
N.A.
80
0
N.A.
0
0
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
86.6
0
N.A.
0
0
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
45
0
0
12
23
0
0
0
0
45
0
12
0
0
% A
% Cys:
12
12
0
0
0
0
0
0
0
12
12
45
56
0
0
% C
% Asp:
12
0
0
0
12
0
0
23
0
0
0
23
0
12
0
% D
% Glu:
12
23
0
0
12
0
56
0
0
0
0
0
0
23
23
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
23
0
0
% F
% Gly:
12
0
45
12
0
0
0
12
0
34
0
0
0
0
56
% G
% His:
0
0
12
0
0
12
12
0
0
0
0
12
0
56
12
% H
% Ile:
0
0
0
23
0
0
23
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
12
0
56
0
0
0
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
45
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
45
12
12
0
34
0
0
0
0
45
0
0
0
0
0
% P
% Gln:
0
0
23
0
0
0
0
12
0
12
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% R
% Ser:
12
0
12
12
0
0
0
12
12
0
12
12
0
0
12
% S
% Thr:
0
0
0
0
34
0
0
45
12
0
12
0
0
12
0
% T
% Val:
0
0
0
0
0
0
12
0
56
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _