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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMEK1
All Species:
30
Human Site:
S783
Identified Species:
55
UniProt:
Q6IN85
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IN85
NP_115949.3
833
95368
S783
G
S
P
G
S
P
G
S
V
P
K
N
T
S
Q
Chimpanzee
Pan troglodytes
XP_001140788
1051
117499
S1001
G
S
P
G
S
P
G
S
V
P
K
N
T
S
Q
Rhesus Macaque
Macaca mulatta
XP_001112386
1020
115840
N972
Q
T
P
P
A
T
S
N
G
S
S
S
K
T
T
Dog
Lupus familis
XP_854423
820
93834
S770
G
S
P
G
S
P
G
S
V
P
K
S
T
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6P2K6
820
93824
S770
G
S
P
G
S
P
G
S
V
P
K
S
T
S
Q
Rat
Rattus norvegicus
NP_001101837
820
93952
S770
V
A
Q
T
T
P
A
S
S
N
G
S
S
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506908
818
93822
S768
G
S
P
G
S
P
G
S
V
S
K
S
T
S
Q
Chicken
Gallus gallus
XP_421321
821
93987
S770
G
S
P
G
S
P
G
S
V
S
K
S
T
S
Q
Frog
Xenopus laevis
Q6INN7
822
94182
S770
G
S
P
E
S
P
G
S
V
S
K
S
T
P
Q
Zebra Danio
Brachydanio rerio
Q5SP90
818
93771
S770
P
G
T
G
A
R
S
S
P
P
S
A
A
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFS5
980
109277
S862
A
A
A
S
L
C
D
S
A
T
V
A
A
V
A
Honey Bee
Apis mellifera
XP_393542
775
88267
E727
N
E
S
P
I
T
S
E
I
N
P
N
S
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40164
858
98034
G810
S
V
N
M
S
T
D
G
F
A
S
N
H
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
59.7
97.8
N.A.
97.7
73.3
N.A.
94.1
96
89.9
87.6
N.A.
49.2
58.7
N.A.
N.A.
Protein Similarity:
100
78
69.7
98.3
N.A.
98.1
85.5
N.A.
95.6
97.2
94.8
93.6
N.A.
66.2
73.5
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
20
N.A.
86.6
86.6
73.3
20
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
100
53.3
N.A.
93.3
93.3
80
26.6
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
0
16
0
8
0
8
8
0
16
16
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
54
8
0
54
0
0
54
8
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
54
0
8
0
8
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
8
0
16
0
31
0
0
0
% N
% Pro:
8
0
62
16
0
62
0
0
8
39
8
0
0
8
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
54
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
54
8
8
62
0
24
77
8
31
24
54
16
54
0
% S
% Thr:
0
8
8
8
8
24
0
0
0
8
0
0
54
16
16
% T
% Val:
8
8
0
0
0
0
0
0
54
0
8
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _