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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMEK1
All Species:
25.45
Human Site:
S826
Identified Species:
46.67
UniProt:
Q6IN85
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IN85
NP_115949.3
833
95368
S826
K
E
D
T
L
P
L
S
K
K
A
K
F
D
S
Chimpanzee
Pan troglodytes
XP_001140788
1051
117499
S1044
K
E
D
T
L
P
L
S
K
K
A
K
F
D
S
Rhesus Macaque
Macaca mulatta
XP_001112386
1020
115840
Dog
Lupus familis
XP_854423
820
93834
S813
K
E
D
T
L
P
L
S
K
K
A
K
F
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P2K6
820
93824
S813
K
E
D
T
L
P
V
S
K
K
A
K
F
E
S
Rat
Rattus norvegicus
NP_001101837
820
93952
R813
E
E
E
E
S
S
P
R
K
R
P
R
L
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506908
818
93822
S811
K
E
E
T
L
S
L
S
K
K
A
K
L
E
S
Chicken
Gallus gallus
XP_421321
821
93987
S813
K
E
E
T
L
P
L
S
K
K
A
K
L
E
S
Frog
Xenopus laevis
Q6INN7
822
94182
T815
K
E
E
R
L
P
L
T
K
K
A
R
L
G
S
Zebra Danio
Brachydanio rerio
Q5SP90
818
93771
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFS5
980
109277
G970
E
E
D
E
Y
S
E
G
P
Q
A
Q
K
R
A
Honey Bee
Apis mellifera
XP_393542
775
88267
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40164
858
98034
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
59.7
97.8
N.A.
97.7
73.3
N.A.
94.1
96
89.9
87.6
N.A.
49.2
58.7
N.A.
N.A.
Protein Similarity:
100
78
69.7
98.3
N.A.
98.1
85.5
N.A.
95.6
97.2
94.8
93.6
N.A.
66.2
73.5
N.A.
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
86.6
20
N.A.
73.3
80
60
0
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
46.6
N.A.
86.6
93.3
80
0
N.A.
46.6
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
39
0
0
0
0
0
0
0
0
0
0
16
0
% D
% Glu:
16
70
31
16
0
0
8
0
0
0
0
0
0
31
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
54
0
0
0
0
0
0
0
62
54
0
47
8
0
0
% K
% Leu:
0
0
0
0
54
0
47
0
0
0
0
0
31
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
47
8
0
8
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
0
8
0
16
0
8
0
% R
% Ser:
0
0
0
0
8
24
0
47
0
0
0
0
0
0
62
% S
% Thr:
0
0
0
47
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _