KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW3
All Species:
21.52
Human Site:
S25
Identified Species:
52.59
UniProt:
Q6IPR3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IPR3
NP_612476.1
259
29794
S25
A
D
L
S
R
K
G
S
V
D
E
D
V
V
E
Chimpanzee
Pan troglodytes
XP_001167649
259
29688
S25
A
D
L
S
R
K
G
S
V
D
E
D
V
V
E
Rhesus Macaque
Macaca mulatta
XP_001100269
258
29422
S25
A
D
L
S
R
K
G
S
V
D
K
D
V
V
E
Dog
Lupus familis
XP_537110
218
24675
Q25
G
I
N
G
F
E
V
Q
K
Q
N
C
C
W
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSA9
257
28557
S25
A
D
L
S
R
K
G
S
V
D
E
D
A
V
E
Rat
Rattus norvegicus
XP_001080203
258
28574
S25
A
D
L
S
R
K
G
S
V
D
E
D
A
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505991
369
41449
V41
M
S
I
P
R
P
C
V
A
W
D
L
I
S
H
Chicken
Gallus gallus
XP_422546
250
27520
A27
R
G
A
L
D
E
R
A
A
G
V
V
R
L
L
Frog
Xenopus laevis
Q641F8
251
28675
S25
T
D
V
S
K
K
G
S
V
D
E
D
I
E
E
Zebra Danio
Brachydanio rerio
Q6DHJ1
251
28779
V25
D
F
S
K
K
G
S
V
D
E
D
I
S
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
91.5
68.7
N.A.
70.2
69.5
N.A.
35.7
52.9
50.1
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
95.3
76
N.A.
80.6
78.7
N.A.
49.3
70.6
72.1
71.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
93.3
93.3
N.A.
6.6
0
66.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
26.6
20
86.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
10
0
0
0
0
10
20
0
0
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
0
% C
% Asp:
10
60
0
0
10
0
0
0
10
60
20
60
0
0
0
% D
% Glu:
0
0
0
0
0
20
0
0
0
10
50
0
0
10
60
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
0
10
60
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
10
20
0
0
% I
% Lys:
0
0
0
10
20
60
0
0
10
0
10
0
0
0
0
% K
% Leu:
0
0
50
10
0
0
0
0
0
0
0
10
0
10
20
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
60
0
10
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
10
60
0
0
10
60
0
0
0
0
10
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
10
20
60
0
10
10
30
50
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _