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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPP All Species: 7.88
Human Site: S132 Identified Species: 57.78
UniProt: Q6IPU0 Number Species: 3
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IPU0 NP_001012267.1 288 33165 S132 I Q N K E R L S S A V T D L N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CZ92 286 33269 S131 M E T K E K K S S I I T D L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q1T7B7 287 32895 S134 V Q N K E N V S A A I T D L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LV50 282 32516 H130 I Q E D N V L H R R V T E L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 68 N.A. N.A. N.A. 46.1 N.A. 36.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. N.A. N.A. 80.9 N.A. N.A. N.A. 63.8 N.A. 54.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. N.A. N.A. 46.6 N.A. N.A. N.A. 60 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 80 N.A. N.A. N.A. 93.3 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 25 50 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 25 0 0 0 0 0 0 0 0 75 0 0 % D
% Glu: 0 25 25 0 75 0 0 0 0 0 0 0 25 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % H
% Ile: 50 0 0 0 0 0 0 0 0 25 50 0 0 0 0 % I
% Lys: 0 0 0 75 0 25 25 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 50 0 0 0 0 0 0 100 0 % L
% Met: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 50 0 25 25 0 0 0 0 0 0 0 0 50 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 25 0 0 25 25 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 75 50 0 0 0 0 0 50 % S
% Thr: 0 0 25 0 0 0 0 0 0 0 0 100 0 0 0 % T
% Val: 25 0 0 0 0 25 25 0 0 0 50 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _