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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPOPL
All Species:
25.76
Human Site:
Y259
Identified Species:
62.96
UniProt:
Q6IQ16
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IQ16
NP_001001664.1
392
44647
Y259
K
E
M
M
R
F
I
Y
T
G
R
A
P
N
L
Chimpanzee
Pan troglodytes
XP_001156368
374
42555
D247
R
V
E
I
N
D
L
D
P
E
V
F
K
E
M
Rhesus Macaque
Macaca mulatta
XP_001091245
392
44601
Y259
K
E
M
M
R
F
I
Y
T
G
R
A
P
N
L
Dog
Lupus familis
XP_533341
392
44573
Y259
K
E
M
M
R
F
I
Y
T
G
K
A
P
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q2M2N2
392
44655
Y259
K
E
M
M
R
F
V
Y
T
G
K
A
P
N
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510032
392
44140
Y259
K
E
M
M
S
F
I
Y
A
G
K
A
P
N
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GR09
392
44625
Y259
K
E
M
M
R
F
I
Y
T
G
G
T
P
H
V
Zebra Danio
Brachydanio rerio
Q5BL35
392
44214
Y259
K
E
M
M
G
F
I
Y
T
G
K
A
P
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFP2
829
89649
D702
R
V
A
I
T
D
V
D
H
E
V
L
K
E
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34568
451
51044
D316
T
N
M
T
T
V
D
D
I
E
P
E
V
M
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.4
99.7
98.7
N.A.
96.1
N.A.
N.A.
92.8
N.A.
84.6
91
N.A.
36.1
N.A.
54.7
N.A.
Protein Similarity:
100
95.4
100
99.4
N.A.
98.4
N.A.
N.A.
96.6
N.A.
92
96.9
N.A.
40.8
N.A.
70
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
86.6
N.A.
N.A.
80
N.A.
73.3
86.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
86.6
N.A.
86.6
93.3
N.A.
26.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
0
0
60
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
20
10
30
0
0
0
0
0
0
0
% D
% Glu:
0
70
10
0
0
0
0
0
0
30
0
10
0
20
0
% E
% Phe:
0
0
0
0
0
70
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
70
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
20
0
0
60
0
10
0
0
0
0
0
0
% I
% Lys:
70
0
0
0
0
0
0
0
0
0
40
0
20
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
60
% L
% Met:
0
0
80
70
0
0
0
0
0
0
0
0
0
10
20
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
0
0
0
60
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
10
0
70
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
0
0
50
0
0
0
0
0
20
0
0
0
10
% R
% Ser:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
10
20
0
0
0
60
0
0
10
0
0
0
% T
% Val:
0
20
0
0
0
10
20
0
0
0
20
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _