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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAPEPLD All Species: 20.91
Human Site: S37 Identified Species: 46
UniProt: Q6IQ20 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IQ20 NP_001116310.1 393 45596 S37 N S G A S D S S R F S R K S F
Chimpanzee Pan troglodytes XP_001158294 466 53476 S110 N S G G S D S S R F S R K S F
Rhesus Macaque Macaca mulatta XP_001086270 393 45647 S37 N S R G S D S S R F S R K S F
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BH82 396 45797 S37 N S G G S V S S R F S R K S F
Rat Rattus norvegicus Q769K2 396 45704 S37 N S G G S E S S R L S R K S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025901 464 52849 S108 G S R G S D T S R A S R K S F
Frog Xenopus laevis NP_001108296 406 46464 C47 S S R S S D S C R S S R K S F
Zebra Danio Brachydanio rerio NP_001074082 364 40875 S39 G R F V N P W S T W H F P S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_500407 355 40247 G38 T N W G G I P G I S D G F K F
Sea Urchin Strong. purpuratus XP_782815 574 64776 R218 D F D I N T S R T K V I C N D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02883 468 54349 E117 L E V L G R F E N P F E E Y R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.4 98.4 N.A. N.A. 88.6 89.9 N.A. N.A. 68.5 73.4 60 N.A. N.A. N.A. 38.1 38.1
Protein Similarity: 100 83.6 98.4 N.A. N.A. 93.6 94.4 N.A. N.A. 76.5 84.4 71.2 N.A. N.A. N.A. 57.7 51.5
P-Site Identity: 100 93.3 86.6 N.A. N.A. 86.6 80 N.A. N.A. 66.6 66.6 13.3 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 93.3 86.6 N.A. N.A. 86.6 86.6 N.A. N.A. 73.3 80 33.3 N.A. N.A. N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % C
% Asp: 10 0 10 0 0 46 0 0 0 0 10 0 0 0 10 % D
% Glu: 0 10 0 0 0 10 0 10 0 0 0 10 10 0 0 % E
% Phe: 0 10 10 0 0 0 10 0 0 37 10 10 10 0 73 % F
% Gly: 19 0 37 55 19 0 0 10 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 10 0 10 0 0 10 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 64 10 0 % K
% Leu: 10 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 46 10 0 0 19 0 0 0 10 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 10 10 0 0 10 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 28 0 0 10 0 10 64 0 0 64 0 0 10 % R
% Ser: 10 64 0 10 64 0 64 64 0 19 64 0 0 73 0 % S
% Thr: 10 0 0 0 0 10 10 0 19 0 0 0 0 0 0 % T
% Val: 0 0 10 10 0 10 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 10 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _