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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB12
All Species:
23.94
Human Site:
S220
Identified Species:
37.62
UniProt:
Q6IQ22
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IQ22
NP_001020471.2
244
27248
S220
L
R
N
E
L
S
N
S
I
L
S
L
Q
P
E
Chimpanzee
Pan troglodytes
XP_522433
267
29486
S242
L
K
S
G
G
R
R
S
G
N
G
N
K
P
P
Rhesus Macaque
Macaca mulatta
XP_001118552
252
28578
S228
L
R
N
E
L
S
N
S
I
L
S
L
Q
P
E
Dog
Lupus familis
XP_537327
290
32457
S266
L
R
N
E
L
S
N
S
I
L
S
L
Q
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P35283
243
27310
S219
L
R
N
E
L
S
N
S
I
L
S
L
Q
P
E
Rat
Rattus norvegicus
P35284
197
22416
P184
L
Q
P
E
P
E
I
P
P
E
L
P
P
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505400
138
15739
L128
E
P
E
I
P
P
E
L
P
P
P
R
P
P
V
Chicken
Gallus gallus
Q5ZIT5
200
22530
G189
E
N
V
D
I
S
S
G
G
G
V
T
G
W
K
Frog
Xenopus laevis
NP_001083268
200
22550
G189
E
N
V
D
I
S
S
G
G
G
V
T
G
W
K
Zebra Danio
Brachydanio rerio
NP_001018466
235
26358
S213
P
S
K
E
L
S
N
S
V
L
S
L
Q
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25228
220
24843
S189
I
C
D
K
M
S
E
S
L
D
A
D
P
T
L
Honey Bee
Apis mellifera
XP_393723
200
22900
D184
K
E
P
Q
D
A
P
D
R
V
T
V
D
R
R
Nematode Worm
Caenorhab. elegans
Q94986
219
24741
S190
I
C
D
K
M
A
E
S
L
D
K
D
P
Q
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28188
203
22630
P185
A
G
N
N
A
R
P
P
T
V
Q
I
R
G
Q
Baker's Yeast
Sacchar. cerevisiae
P07560
215
23487
N187
I
Q
E
K
I
D
S
N
K
L
V
G
V
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.7
71.8
66.5
N.A.
95.9
77.8
N.A.
50.8
41.3
41.7
83.1
N.A.
38.1
41.7
40.5
N.A.
Protein Similarity:
100
55.4
74.2
70.6
N.A.
96.7
79
N.A.
53.6
60.2
60.6
89.7
N.A.
58.2
59.8
59.4
N.A.
P-Site Identity:
100
20
100
100
N.A.
100
20
N.A.
6.6
6.6
6.6
73.3
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
26.6
N.A.
6.6
33.3
33.3
80
N.A.
53.3
33.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.9
40.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.5
60.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
14
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
14
7
7
0
7
0
14
0
14
7
0
0
% D
% Glu:
20
7
14
40
0
7
20
0
0
7
0
0
0
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
7
7
0
0
14
20
14
7
7
14
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
7
20
0
7
0
27
0
0
7
0
0
0
% I
% Lys:
7
7
7
20
0
0
0
0
7
0
7
0
7
0
14
% K
% Leu:
40
0
0
0
34
0
0
7
14
40
7
34
0
0
7
% L
% Met:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
14
34
7
0
0
34
7
0
7
0
7
0
0
7
% N
% Pro:
7
7
14
0
14
7
14
14
14
7
7
7
27
54
7
% P
% Gln:
0
14
0
7
0
0
0
0
0
0
7
0
34
7
14
% Q
% Arg:
0
27
0
0
0
14
7
0
7
0
0
7
7
7
14
% R
% Ser:
0
7
7
0
0
54
20
54
0
0
34
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
7
14
0
7
0
% T
% Val:
0
0
14
0
0
0
0
0
7
14
20
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _