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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB12
All Species:
7.27
Human Site:
S25
Identified Species:
11.43
UniProt:
Q6IQ22
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IQ22
NP_001020471.2
244
27248
S25
G
A
G
S
P
A
L
S
G
G
Q
G
R
R
R
Chimpanzee
Pan troglodytes
XP_522433
267
29486
F19
G
G
V
P
P
L
L
F
P
G
A
W
A
E
R
Rhesus Macaque
Macaca mulatta
XP_001118552
252
28578
D9
T
E
V
C
E
G
K
D
C
P
R
Q
L
S
S
Dog
Lupus familis
XP_537327
290
32457
L68
G
A
D
G
P
L
L
L
P
Q
M
P
R
W
R
Cat
Felis silvestris
Mouse
Mus musculus
P35283
243
27310
S24
G
A
V
S
P
A
L
S
G
G
Q
A
R
R
R
Rat
Rattus norvegicus
P35284
197
22416
T9
G
S
R
G
V
G
K
T
S
L
M
E
R
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505400
138
15739
Chicken
Gallus gallus
Q5ZIT5
200
22530
L9
A
K
K
T
Y
D
L
L
F
K
L
L
L
I
G
Frog
Xenopus laevis
NP_001083268
200
22550
L9
A
K
K
T
Y
D
L
L
F
K
L
L
L
I
G
Zebra Danio
Brachydanio rerio
NP_001018466
235
26358
G19
G
G
G
S
P
A
V
G
A
S
Q
R
R
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25228
220
24843
W9
A
S
G
G
D
P
K
W
Q
K
D
A
A
D
Q
Honey Bee
Apis mellifera
XP_393723
200
22900
L9
A
K
K
T
Y
D
L
L
F
K
L
L
L
I
G
Nematode Worm
Caenorhab. elegans
Q94986
219
24741
G9
A
A
G
G
Q
P
Q
G
A
T
P
G
Q
P
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28188
203
22630
F9
N
P
E
Y
D
Y
L
F
K
L
L
L
I
G
D
Baker's Yeast
Sacchar. cerevisiae
P07560
215
23487
S10
G
L
R
T
V
S
A
S
S
G
N
G
K
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.7
71.8
66.5
N.A.
95.9
77.8
N.A.
50.8
41.3
41.7
83.1
N.A.
38.1
41.7
40.5
N.A.
Protein Similarity:
100
55.4
74.2
70.6
N.A.
96.7
79
N.A.
53.6
60.2
60.6
89.7
N.A.
58.2
59.8
59.4
N.A.
P-Site Identity:
100
33.3
0
40
N.A.
86.6
13.3
N.A.
0
6.6
6.6
53.3
N.A.
6.6
6.6
20
N.A.
P-Site Similarity:
100
33.3
6.6
40
N.A.
86.6
26.6
N.A.
0
13.3
13.3
66.6
N.A.
20
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.9
40.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.5
60.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
27
0
0
0
20
7
0
14
0
7
14
14
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
14
20
0
7
0
0
7
0
0
7
14
% D
% Glu:
0
7
7
0
7
0
0
0
0
0
0
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
14
20
0
0
0
0
7
0
% F
% Gly:
47
14
27
27
0
14
0
14
14
27
0
20
0
7
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
7
20
0
% I
% Lys:
0
20
20
0
0
0
20
0
7
27
0
0
7
0
7
% K
% Leu:
0
7
0
0
0
14
54
27
0
14
27
27
27
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
7
0
7
34
14
0
0
14
7
7
7
0
7
0
% P
% Gln:
0
0
0
0
7
0
7
0
7
7
20
7
7
0
7
% Q
% Arg:
0
0
14
0
0
0
0
0
0
0
7
7
34
20
27
% R
% Ser:
0
14
0
20
0
7
0
20
14
7
0
0
0
14
7
% S
% Thr:
7
0
0
27
0
0
0
7
0
7
0
0
0
0
7
% T
% Val:
0
0
20
0
14
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
7
0
7
0
% W
% Tyr:
0
0
0
7
20
7
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _