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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB12 All Species: 18.18
Human Site: S57 Identified Species: 28.57
UniProt: Q6IQ22 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IQ22 NP_001020471.2 244 27248 S57 S R G V G K T S L M E R F T D
Chimpanzee Pan troglodytes XP_522433 267 29486 C87 D S G V G K T C L I I R F A E
Rhesus Macaque Macaca mulatta XP_001118552 252 28578 T65 L F L C G H R T T H K C G H L
Dog Lupus familis XP_537327 290 32457 A103 P A W Q R C L A E A R Q Y C D
Cat Felis silvestris
Mouse Mus musculus P35283 243 27310 S56 S R G V G K T S L M E R F T D
Rat Rattus norvegicus P35284 197 22416 T36 G V D F K I K T V E L R G K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505400 138 15739
Chicken Gallus gallus Q5ZIT5 200 22530 T36 F S D D A F N T T F I S T I G
Frog Xenopus laevis NP_001083268 200 22550 T36 F S D D A F N T T F I S T I G
Zebra Danio Brachydanio rerio NP_001018466 235 26358 S50 S R G V G K T S L M E R F T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25228 220 24843 S36 N S S V G K T S F L F R Y A D
Honey Bee Apis mellifera XP_393723 200 22900 T36 F S D D A F S T T F I S T I G
Nematode Worm Caenorhab. elegans Q94986 219 24741 S37 N S S V G K T S F L F R Y C D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28188 203 22630 E35 F S D D S Y V E S Y I S T I G
Baker's Yeast Sacchar. cerevisiae P07560 215 23487 C35 D S G V G K S C L L V R F V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.7 71.8 66.5 N.A. 95.9 77.8 N.A. 50.8 41.3 41.7 83.1 N.A. 38.1 41.7 40.5 N.A.
Protein Similarity: 100 55.4 74.2 70.6 N.A. 96.7 79 N.A. 53.6 60.2 60.6 89.7 N.A. 58.2 59.8 59.4 N.A.
P-Site Identity: 100 53.3 6.6 6.6 N.A. 100 6.6 N.A. 0 0 0 100 N.A. 46.6 0 46.6 N.A.
P-Site Similarity: 100 66.6 20 26.6 N.A. 100 20 N.A. 0 6.6 6.6 100 N.A. 66.6 13.3 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.9 40.9 N.A.
Protein Similarity: N.A. N.A. N.A. 56.5 60.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 20 0 0 7 0 7 0 0 0 14 0 % A
% Cys: 0 0 0 7 0 7 0 14 0 0 0 7 0 14 0 % C
% Asp: 14 0 34 27 0 0 0 0 0 0 0 0 0 0 40 % D
% Glu: 0 0 0 0 0 0 0 7 7 7 20 0 0 0 14 % E
% Phe: 27 7 0 7 0 20 0 0 14 20 14 0 34 0 0 % F
% Gly: 7 0 34 0 54 0 0 0 0 0 0 0 14 0 27 % G
% His: 0 0 0 0 0 7 0 0 0 7 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 7 34 0 0 27 0 % I
% Lys: 0 0 0 0 7 47 7 0 0 0 7 0 0 7 7 % K
% Leu: 7 0 7 0 0 0 7 0 34 20 7 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % M
% Asn: 14 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 20 0 0 7 0 7 0 0 0 7 54 0 0 0 % R
% Ser: 20 54 14 0 7 0 14 34 7 0 0 27 0 0 0 % S
% Thr: 0 0 0 0 0 0 40 34 27 0 0 0 27 20 0 % T
% Val: 0 7 0 47 0 0 7 0 7 0 7 0 0 7 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 7 0 0 20 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _