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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB12 All Species: 33.33
Human Site: T125 Identified Species: 52.38
UniProt: Q6IQ22 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IQ22 NP_001020471.2 244 27248 T125 I I L V Y D I T K K E T F D D
Chimpanzee Pan troglodytes XP_522433 267 29486 T155 I I L V Y D I T D E K S F E N
Rhesus Macaque Macaca mulatta XP_001118552 252 28578 T133 I I L V Y D I T K K E T F D D
Dog Lupus familis XP_537327 290 32457 T171 I I L V Y D I T K K E T F D D
Cat Felis silvestris
Mouse Mus musculus P35283 243 27310 T124 I I L V Y D I T K K E T F D D
Rat Rattus norvegicus P35284 197 22416 L104 A S E D A E L L L A G N K L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505400 138 15739 L51 L L L V G N K L D C E T D R E
Chicken Gallus gallus Q5ZIT5 200 22530 L104 F E N I S K W L R N I D E H A
Frog Xenopus laevis NP_001083268 200 22550 L104 F E N I S K W L R N I D E H A
Zebra Danio Brachydanio rerio NP_001018466 235 26358 T118 I V L V Y D I T K Q E T F E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25228 220 24843 T104 F I L M Y D V T N E D S F N S
Honey Bee Apis mellifera XP_393723 200 22900 L104 F E N I V K W L R N I D E H A
Nematode Worm Caenorhab. elegans Q94986 219 24741 T105 F I L M Y D I T N E E S F N S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28188 203 22630 L103 F N N V K Q W L S E I D R Y A
Baker's Yeast Sacchar. cerevisiae P07560 215 23487 T103 I I L V Y D V T D E R T F T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.7 71.8 66.5 N.A. 95.9 77.8 N.A. 50.8 41.3 41.7 83.1 N.A. 38.1 41.7 40.5 N.A.
Protein Similarity: 100 55.4 74.2 70.6 N.A. 96.7 79 N.A. 53.6 60.2 60.6 89.7 N.A. 58.2 59.8 59.4 N.A.
P-Site Identity: 100 60 100 100 N.A. 100 6.6 N.A. 26.6 0 0 80 N.A. 40 0 53.3 N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 20 N.A. 53.3 13.3 13.3 100 N.A. 80 13.3 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.9 40.9 N.A.
Protein Similarity: N.A. N.A. N.A. 56.5 60.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 7 0 0 0 0 7 0 0 0 0 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 60 0 0 20 0 7 27 7 27 40 % D
% Glu: 0 20 7 0 0 7 0 0 0 34 47 0 20 14 7 % E
% Phe: 40 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % H
% Ile: 47 54 0 20 0 0 47 0 0 0 27 0 0 0 0 % I
% Lys: 0 0 0 0 7 20 7 0 34 27 7 0 7 0 0 % K
% Leu: 7 7 67 0 0 0 7 40 7 0 0 0 0 7 0 % L
% Met: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 27 0 0 7 0 0 14 20 0 7 0 14 14 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 20 0 7 0 7 7 0 % R
% Ser: 0 7 0 0 14 0 0 0 7 0 0 20 0 0 14 % S
% Thr: 0 0 0 0 0 0 0 60 0 0 0 47 0 7 0 % T
% Val: 0 7 0 60 7 0 14 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 60 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _