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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB12
All Species:
20.91
Human Site:
T161
Identified Species:
32.86
UniProt:
Q6IQ22
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IQ22
NP_001020471.2
244
27248
T161
G
N
K
L
D
C
E
T
D
R
E
I
T
R
Q
Chimpanzee
Pan troglodytes
XP_522433
267
29486
A191
G
N
K
C
D
M
E
A
K
R
K
V
Q
K
E
Rhesus Macaque
Macaca mulatta
XP_001118552
252
28578
T169
G
N
K
L
D
C
E
T
D
R
E
I
T
R
Q
Dog
Lupus familis
XP_537327
290
32457
T207
G
N
K
L
D
C
E
T
D
R
E
I
T
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
P35283
243
27310
T160
G
N
K
L
D
C
E
T
D
R
E
I
S
R
Q
Rat
Rattus norvegicus
P35284
197
22416
D142
L
S
E
P
S
A
K
D
N
F
N
V
D
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505400
138
15739
N86
A
S
A
K
D
N
F
N
V
D
E
I
F
L
K
Chicken
Gallus gallus
Q5ZIT5
200
22530
I140
P
K
A
K
G
E
Q
I
A
R
E
H
G
I
R
Frog
Xenopus laevis
NP_001083268
200
22550
I140
P
K
A
K
G
E
Q
I
A
R
E
H
G
I
R
Zebra Danio
Brachydanio rerio
NP_001018466
235
26358
S154
G
N
K
L
D
C
E
S
D
R
A
I
S
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25228
220
24843
D140
G
N
K
C
D
M
E
D
Q
R
V
I
S
F
E
Honey Bee
Apis mellifera
XP_393723
200
22900
I140
S
T
E
R
G
E
A
I
A
R
E
H
G
I
R
Nematode Worm
Caenorhab. elegans
Q94986
219
24741
S141
G
N
K
C
D
M
D
S
E
R
V
V
S
M
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28188
203
22630
F139
P
Y
E
T
A
K
A
F
A
D
E
I
G
I
P
Baker's Yeast
Sacchar. cerevisiae
P07560
215
23487
E138
V
G
N
K
S
D
M
E
T
R
V
V
T
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.7
71.8
66.5
N.A.
95.9
77.8
N.A.
50.8
41.3
41.7
83.1
N.A.
38.1
41.7
40.5
N.A.
Protein Similarity:
100
55.4
74.2
70.6
N.A.
96.7
79
N.A.
53.6
60.2
60.6
89.7
N.A.
58.2
59.8
59.4
N.A.
P-Site Identity:
100
40
100
100
N.A.
93.3
0
N.A.
20
13.3
13.3
80
N.A.
46.6
13.3
33.3
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
100
33.3
N.A.
33.3
26.6
26.6
93.3
N.A.
60
26.6
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.9
40.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.5
60.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
20
0
7
7
14
7
27
0
7
0
0
7
0
% A
% Cys:
0
0
0
20
0
34
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
60
7
7
14
34
14
0
0
7
0
14
% D
% Glu:
0
0
20
0
0
20
47
7
7
0
60
0
0
7
14
% E
% Phe:
0
0
0
0
0
0
7
7
0
7
0
0
7
7
0
% F
% Gly:
54
7
0
0
20
0
0
0
0
0
0
0
27
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
20
0
0
0
54
0
27
7
% I
% Lys:
0
14
54
27
0
7
7
0
7
0
7
0
0
7
7
% K
% Leu:
7
0
0
34
0
0
0
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
20
7
0
0
0
0
0
0
7
0
% M
% Asn:
0
54
7
0
0
7
0
7
7
0
7
0
0
0
0
% N
% Pro:
20
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
14
0
7
0
0
0
7
0
34
% Q
% Arg:
0
0
0
7
0
0
0
0
0
80
0
0
0
34
20
% R
% Ser:
7
14
0
0
14
0
0
14
0
0
0
0
27
0
0
% S
% Thr:
0
7
0
7
0
0
0
27
7
0
0
0
27
0
0
% T
% Val:
7
0
0
0
0
0
0
0
7
0
20
27
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _