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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB12 All Species: 24.55
Human Site: T166 Identified Species: 38.57
UniProt: Q6IQ22 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IQ22 NP_001020471.2 244 27248 T166 C E T D R E I T R Q Q G E K F
Chimpanzee Pan troglodytes XP_522433 267 29486 Q196 M E A K R K V Q K E Q A D K L
Rhesus Macaque Macaca mulatta XP_001118552 252 28578 T174 C E T D R E I T R Q Q G E K F
Dog Lupus familis XP_537327 290 32457 T212 C E T D R E I T R Q Q G E K F
Cat Felis silvestris
Mouse Mus musculus P35283 243 27310 S165 C E T D R E I S R Q Q G E K F
Rat Rattus norvegicus P35284 197 22416 D147 A K D N F N V D E I F L K L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505400 138 15739 F91 N F N V D E I F L K L V D D I
Chicken Gallus gallus Q5ZIT5 200 22530 G145 E Q I A R E H G I R F F E T S
Frog Xenopus laevis NP_001083268 200 22550 G145 E Q I A R E H G I R F F E T S
Zebra Danio Brachydanio rerio NP_001018466 235 26358 S159 C E S D R A I S R Q Q A E R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25228 220 24843 S145 M E D Q R V I S F E R G R Q L
Honey Bee Apis mellifera XP_393723 200 22900 G145 E A I A R E H G I R F M E T S
Nematode Worm Caenorhab. elegans Q94986 219 24741 S146 M D S E R V V S M D R G R Q L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28188 203 22630 G144 K A F A D E I G I P F M E T S
Baker's Yeast Sacchar. cerevisiae P07560 215 23487 T143 D M E T R V V T A D Q G E A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.7 71.8 66.5 N.A. 95.9 77.8 N.A. 50.8 41.3 41.7 83.1 N.A. 38.1 41.7 40.5 N.A.
Protein Similarity: 100 55.4 74.2 70.6 N.A. 96.7 79 N.A. 53.6 60.2 60.6 89.7 N.A. 58.2 59.8 59.4 N.A.
P-Site Identity: 100 26.6 100 100 N.A. 93.3 0 N.A. 13.3 20 20 66.6 N.A. 26.6 20 13.3 N.A.
P-Site Similarity: 100 60 100 100 N.A. 100 26.6 N.A. 26.6 33.3 33.3 86.6 N.A. 53.3 26.6 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.9 40.9 N.A.
Protein Similarity: N.A. N.A. N.A. 56.5 60.2 N.A.
P-Site Identity: N.A. N.A. N.A. 20 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 7 27 0 7 0 0 7 0 0 14 0 7 0 % A
% Cys: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 14 34 14 0 0 7 0 14 0 0 14 7 0 % D
% Glu: 20 47 7 7 0 60 0 0 7 14 0 0 67 0 0 % E
% Phe: 0 7 7 0 7 0 0 7 7 0 34 14 0 0 34 % F
% Gly: 0 0 0 0 0 0 0 27 0 0 0 47 0 0 0 % G
% His: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 0 54 0 27 7 0 0 0 0 7 % I
% Lys: 7 7 0 7 0 7 0 0 7 7 0 0 7 34 0 % K
% Leu: 0 0 0 0 0 0 0 0 7 0 7 7 0 7 27 % L
% Met: 20 7 0 0 0 0 0 0 7 0 0 14 0 0 0 % M
% Asn: 7 0 7 7 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % P
% Gln: 0 14 0 7 0 0 0 7 0 34 47 0 0 14 0 % Q
% Arg: 0 0 0 0 80 0 0 0 34 20 14 0 14 7 0 % R
% Ser: 0 0 14 0 0 0 0 27 0 0 0 0 0 0 27 % S
% Thr: 0 0 27 7 0 0 0 27 0 0 0 0 0 27 0 % T
% Val: 0 0 0 7 0 20 27 0 0 0 0 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _