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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHA7 All Species: 18.18
Human Site: S226 Identified Species: 50
UniProt: Q6IQ23 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IQ23 NP_778228.3 1121 127135 S226 V A P E D R I S R K Y S F K A
Chimpanzee Pan troglodytes XP_508305 1320 149097 F216 S G M R T Y Y F S A D T Q E D
Rhesus Macaque Macaca mulatta XP_001086202 1430 161302 S268 V A P E D R I S R K Y S F K A
Dog Lupus familis XP_534076 1237 139350 S342 V A P E D R I S R K Y S F K A
Cat Felis silvestris
Mouse Mus musculus Q3UIL6 1118 126724 S225 V A P E D R I S R K Y S F K A
Rat Rattus norvegicus P60669 779 85624
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513654 574 63754
Chicken Gallus gallus XP_421001 1256 142432 Y212 H S G M R T Y Y F S A D T Q E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001344241 1266 142843 S225 V G P E D H I S R K Y A F K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80 77.2 82.1 N.A. 90.1 25.8 N.A. 21.8 59.5 N.A. 51.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 80.5 77.9 85.6 N.A. 94.3 36.6 N.A. 33.5 69.9 N.A. 65 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. 0 0 N.A. 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 0 N.A. 0 13.3 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 45 0 0 0 0 0 0 0 12 12 12 0 0 56 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 56 0 0 0 0 0 12 12 0 0 12 % D
% Glu: 0 0 0 56 0 0 0 0 0 0 0 0 0 12 12 % E
% Phe: 0 0 0 0 0 0 0 12 12 0 0 0 56 0 0 % F
% Gly: 0 23 12 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 56 0 0 0 56 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 56 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % Q
% Arg: 0 0 0 12 12 45 0 0 56 0 0 0 0 0 0 % R
% Ser: 12 12 0 0 0 0 0 56 12 12 0 45 0 0 0 % S
% Thr: 0 0 0 0 12 12 0 0 0 0 0 12 12 0 0 % T
% Val: 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 23 12 0 0 56 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _