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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHA7
All Species:
16.97
Human Site:
S689
Identified Species:
46.67
UniProt:
Q6IQ23
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IQ23
NP_778228.3
1121
127135
S689
K
P
V
K
I
A
E
S
D
T
D
V
K
L
S
Chimpanzee
Pan troglodytes
XP_508305
1320
149097
Q655
K
L
S
I
F
C
E
Q
D
R
V
L
Q
D
L
Rhesus Macaque
Macaca mulatta
XP_001086202
1430
161302
S731
K
P
V
K
I
A
E
S
D
I
D
V
K
L
S
Dog
Lupus familis
XP_534076
1237
139350
S805
K
P
V
K
I
A
E
S
D
I
D
V
K
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UIL6
1118
126724
S686
K
P
M
K
I
A
E
S
D
I
D
V
K
L
S
Rat
Rattus norvegicus
P60669
779
85624
D378
L
T
K
L
C
G
Q
D
R
L
L
R
Q
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513654
574
63754
Q173
M
G
E
A
A
R
V
Q
I
P
P
T
Q
R
S
Chicken
Gallus gallus
XP_421001
1256
142432
V652
D
I
D
V
K
L
S
V
F
C
E
Q
D
R
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001344241
1266
142843
S681
R
P
V
K
I
A
E
S
D
I
D
V
K
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
77.2
82.1
N.A.
90.1
25.8
N.A.
21.8
59.5
N.A.
51.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
77.9
85.6
N.A.
94.3
36.6
N.A.
33.5
69.9
N.A.
65
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
93.3
93.3
N.A.
86.6
6.6
N.A.
6.6
0
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
93.3
93.3
N.A.
93.3
20
N.A.
13.3
6.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
56
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
12
0
0
0
12
0
0
0
0
0
% C
% Asp:
12
0
12
0
0
0
0
12
67
0
56
0
12
12
0
% D
% Glu:
0
0
12
0
0
0
67
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
12
56
0
0
0
12
45
0
0
0
0
12
% I
% Lys:
56
0
12
56
12
0
0
0
0
0
0
0
56
0
0
% K
% Leu:
12
12
0
12
0
12
0
0
0
12
12
12
0
67
12
% L
% Met:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
56
0
0
0
0
0
0
0
12
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
23
0
0
0
12
34
0
12
% Q
% Arg:
12
0
0
0
0
12
0
0
12
12
0
12
0
23
0
% R
% Ser:
0
0
12
0
0
0
12
56
0
0
0
0
0
0
67
% S
% Thr:
0
12
0
0
0
0
0
0
0
12
0
12
0
0
0
% T
% Val:
0
0
45
12
0
0
12
12
0
0
12
56
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _