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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND5A
All Species:
21.21
Human Site:
S1085
Identified Species:
51.85
UniProt:
Q6IQ26
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IQ26
NP_056028.2
1287
147095
S1085
R
T
P
P
L
Q
Q
S
P
S
V
I
R
R
L
Chimpanzee
Pan troglodytes
XP_508914
1287
147087
S1085
R
T
P
P
L
Q
Q
S
P
S
V
I
R
R
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534048
1350
153085
S1148
R
T
P
P
L
Q
Q
S
P
S
V
I
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAL8
1287
146635
S1085
R
T
P
P
L
Q
Q
S
P
S
V
I
R
R
L
Rat
Rattus norvegicus
NP_001101016
1287
146619
S1085
R
T
P
P
L
Q
Q
S
P
S
V
I
R
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235265
1482
166462
K1275
C
R
T
P
P
Q
Q
K
S
P
T
T
A
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NXD8
1311
147682
R1104
S
K
T
P
P
L
Q
R
S
P
S
Q
I
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647620
1449
163365
P1226
G
S
D
T
R
T
P
P
R
T
R
S
P
S
V
Honey Bee
Apis mellifera
XP_395592
1282
146285
S1091
S
T
P
P
R
C
R
S
P
S
I
P
R
R
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781573
1628
184518
R1072
W
G
S
N
T
T
P
R
R
T
H
T
R
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
93.9
N.A.
97.8
97.6
N.A.
N.A.
63.5
N.A.
66
N.A.
38.9
46.6
N.A.
35.5
Protein Similarity:
100
100
N.A.
94.6
N.A.
98.9
98.9
N.A.
N.A.
73.9
N.A.
77.9
N.A.
55.6
64.4
N.A.
50
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
26.6
N.A.
20
N.A.
0
53.3
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
26.6
N.A.
20
N.A.
20
66.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
50
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
50
10
0
0
0
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
60
80
20
0
20
10
60
20
0
10
10
0
10
% P
% Gln:
0
0
0
0
0
60
70
0
0
0
0
10
0
0
0
% Q
% Arg:
50
10
0
0
20
0
10
20
20
0
10
0
70
90
20
% R
% Ser:
20
10
10
0
0
0
0
60
20
60
10
10
0
10
10
% S
% Thr:
0
60
20
10
10
20
0
0
0
20
10
20
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _