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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND5A
All Species:
14.24
Human Site:
S175
Identified Species:
34.81
UniProt:
Q6IQ26
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IQ26
NP_056028.2
1287
147095
S175
P
A
D
D
R
D
Q
S
S
M
E
D
G
E
D
Chimpanzee
Pan troglodytes
XP_508914
1287
147087
S175
P
A
D
D
R
D
Q
S
S
M
E
D
G
E
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534048
1350
153085
G238
S
A
D
G
R
D
H
G
G
M
E
D
G
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAL8
1287
146635
S175
L
A
D
G
G
D
Q
S
G
M
E
D
G
E
G
Rat
Rattus norvegicus
NP_001101016
1287
146619
S175
L
A
D
G
G
D
Q
S
G
M
E
D
G
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235265
1482
166462
S368
C
S
M
D
S
L
A
S
S
I
D
E
G
D
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NXD8
1311
147682
S186
S
M
D
S
L
S
S
S
L
D
D
V
D
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647620
1449
163365
Q208
H
S
L
S
R
V
K
Q
D
G
P
V
S
R
S
Honey Bee
Apis mellifera
XP_395592
1282
146285
L169
S
L
P
R
H
F
K
L
S
A
H
S
P
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781573
1628
184518
F170
F
A
R
A
A
R
K
F
L
E
Q
L
F
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
93.9
N.A.
97.8
97.6
N.A.
N.A.
63.5
N.A.
66
N.A.
38.9
46.6
N.A.
35.5
Protein Similarity:
100
100
N.A.
94.6
N.A.
98.9
98.9
N.A.
N.A.
73.9
N.A.
77.9
N.A.
55.6
64.4
N.A.
50
P-Site Identity:
100
100
N.A.
60
N.A.
66.6
66.6
N.A.
N.A.
26.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
60
N.A.
66.6
66.6
N.A.
N.A.
60
N.A.
20
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
10
10
0
10
0
0
10
0
0
0
0
20
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
60
30
0
50
0
0
10
10
20
50
10
10
20
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
50
10
0
60
0
% E
% Phe:
10
0
0
0
0
10
0
10
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
30
20
0
0
10
30
10
0
0
60
0
30
% G
% His:
10
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% K
% Leu:
20
10
10
0
10
10
0
10
20
0
0
10
0
0
0
% L
% Met:
0
10
10
0
0
0
0
0
0
50
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
0
10
0
0
0
0
0
0
0
10
0
10
0
10
% P
% Gln:
0
0
0
0
0
0
40
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
10
40
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
30
20
0
20
10
10
10
60
40
0
0
10
10
20
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
20
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _