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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C1orf55
All Species:
12.12
Human Site:
T274
Identified Species:
20.51
UniProt:
Q6IQ49
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IQ49
NP_689821.3
451
49742
T274
Q
R
A
R
V
V
N
T
D
H
G
S
P
E
Q
Chimpanzee
Pan troglodytes
XP_514239
451
49780
T274
Q
R
A
R
V
V
N
T
D
H
G
S
P
E
Q
Rhesus Macaque
Macaca mulatta
XP_001089101
339
37264
S198
E
S
K
E
H
M
E
S
R
I
V
T
E
T
E
Dog
Lupus familis
XP_537233
453
48555
Q275
S
V
P
S
A
A
S
Q
S
P
E
P
P
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1J5
448
48562
T277
P
R
S
S
A
S
G
T
H
S
E
S
P
E
K
Rat
Rattus norvegicus
Q5BJN8
448
48065
T275
V
Q
S
S
G
S
G
T
R
S
E
S
P
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512746
480
52145
E305
P
P
A
E
E
K
G
E
D
H
M
E
T
E
E
Chicken
Gallus gallus
XP_419383
447
48877
A270
H
S
P
A
A
S
A
A
E
E
E
A
L
Q
Q
Frog
Xenopus laevis
Q6NRI5
454
49344
G285
E
S
D
N
I
L
E
G
P
S
S
S
A
G
S
Zebra Danio
Brachydanio rerio
Q7T293
467
51362
Q267
P
A
Q
R
K
H
N
Q
E
E
L
Q
K
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651207
232
26246
R91
T
T
N
R
E
A
C
R
D
L
S
G
R
R
L
Honey Bee
Apis mellifera
XP_396921
269
30583
K128
E
A
A
E
R
K
K
K
K
L
E
R
L
C
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785872
375
41543
L213
F
K
K
H
C
M
W
L
G
I
E
G
D
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130707
447
47910
S273
S
V
S
G
S
S
H
S
E
G
E
S
S
G
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
69.1
68.4
N.A.
65.4
65.8
N.A.
52.9
41.9
47.7
45.8
N.A.
23
25.9
N.A.
31.7
Protein Similarity:
100
99.3
71.4
78.5
N.A.
75.6
76.9
N.A.
64.1
57.2
65.1
60.8
N.A.
36.8
41
N.A.
50.1
P-Site Identity:
100
100
0
6.6
N.A.
33.3
20
N.A.
26.6
6.6
6.6
13.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
33.3
13.3
N.A.
46.6
46.6
N.A.
33.3
26.6
26.6
20
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
28.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
44.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
29
8
22
15
8
8
0
0
0
8
8
0
8
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
29
0
0
0
8
0
8
% D
% Glu:
22
0
0
22
15
0
15
8
22
15
50
8
8
36
36
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
22
8
8
8
15
15
0
15
0
% G
% His:
8
0
0
8
8
8
8
0
8
22
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
15
0
0
0
0
0
% I
% Lys:
0
8
15
0
8
15
8
8
8
0
0
0
8
8
8
% K
% Leu:
0
0
0
0
0
8
0
8
0
15
8
0
15
0
8
% L
% Met:
0
0
0
0
0
15
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
22
0
0
0
0
0
0
0
0
% N
% Pro:
22
8
15
0
0
0
0
0
8
8
0
8
36
8
0
% P
% Gln:
15
8
8
0
0
0
0
15
0
0
0
8
0
8
22
% Q
% Arg:
0
22
0
29
8
0
0
8
15
0
0
8
8
15
0
% R
% Ser:
15
22
22
22
8
29
8
15
8
22
15
43
8
0
8
% S
% Thr:
8
8
0
0
0
0
0
29
0
0
0
8
8
8
8
% T
% Val:
8
15
0
0
15
15
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _