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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF5AL1
All Species:
59.39
Human Site:
S44
Identified Species:
93.33
UniProt:
Q6IS14
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IS14
NP_001093162.1
154
16773
S44
P
C
K
I
V
E
M
S
A
S
K
T
G
K
H
Chimpanzee
Pan troglodytes
XP_001174773
286
30517
S176
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Rhesus Macaque
Macaca mulatta
XP_001118011
190
21255
S80
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_001472697
357
39965
S44
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q07460
153
16702
S44
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Frog
Xenopus laevis
NP_001080536
154
16686
S44
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Zebra Danio
Brachydanio rerio
NP_998350
155
16861
S45
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GU68
159
17573
S45
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Honey Bee
Apis mellifera
XP_624951
160
17574
S46
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Nematode Worm
Caenorhab. elegans
Q20751
161
17935
S48
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Sea Urchin
Strong. purpuratus
XP_785877
156
17276
S46
P
C
K
I
V
E
M
S
T
S
K
T
G
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P80639
160
17478
S47
P
C
K
V
V
E
V
S
T
S
K
T
G
K
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI91
158
17342
S45
P
C
K
V
V
E
V
S
T
S
K
T
G
K
H
Baker's Yeast
Sacchar. cerevisiae
P23301
157
17096
S45
P
C
K
I
V
D
M
S
T
S
K
T
G
K
H
Red Bread Mold
Neurospora crassa
P38672
163
18017
S51
P
C
K
I
V
D
M
S
T
S
K
T
G
K
H
Conservation
Percent
Protein Identity:
100
52.7
79.4
N.A.
N.A.
39.7
N.A.
N.A.
N.A.
82.4
81.1
80
N.A.
64.7
66.8
59
63.4
Protein Similarity:
100
52.7
79.4
N.A.
N.A.
41.4
N.A.
N.A.
N.A.
90.2
91.5
90.3
N.A.
80.5
79.3
73.9
77.5
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
93.3
93.3
93.3
N.A.
93.3
93.3
93.3
93.3
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
93.3
93.3
93.3
N.A.
93.3
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
51.2
N.A.
53.8
60.5
58.2
Protein Similarity:
N.A.
71.2
N.A.
74
80.8
73.6
P-Site Identity:
N.A.
80
N.A.
80
86.6
86.6
P-Site Similarity:
N.A.
93.3
N.A.
93.3
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
87
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
0
0
0
87
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
100
0
0
0
0
0
0
0
100
0
0
100
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
87
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
100
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
94
0
0
100
0
0
0
% T
% Val:
0
0
0
14
100
0
14
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _