Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF5AL1 All Species: 59.39
Human Site: T48 Identified Species: 93.33
UniProt: Q6IS14 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IS14 NP_001093162.1 154 16773 T48 V E M S A S K T G K H G H A K
Chimpanzee Pan troglodytes XP_001174773 286 30517 T180 V E M S T S K T G K H G H A K
Rhesus Macaque Macaca mulatta XP_001118011 190 21255 T84 V E M S T S K T G K H G H A K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus XP_001472697 357 39965 T48 V E M S T S K T G K H G H A K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q07460 153 16702 T48 V E M S T S K T G K H G H A K
Frog Xenopus laevis NP_001080536 154 16686 T48 V E M S T S K T G K H G H A K
Zebra Danio Brachydanio rerio NP_998350 155 16861 T49 V E M S T S K T G K H G H A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GU68 159 17573 T49 V E M S T S K T G K H G H A K
Honey Bee Apis mellifera XP_624951 160 17574 T50 V E M S T S K T G K H G H A K
Nematode Worm Caenorhab. elegans Q20751 161 17935 T52 V E M S T S K T G K H G H A K
Sea Urchin Strong. purpuratus XP_785877 156 17276 T50 V E M S T S K T G K H G H A K
Poplar Tree Populus trichocarpa
Maize Zea mays P80639 160 17478 T51 V E V S T S K T G K H G H A K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XI91 158 17342 T49 V E V S T S K T G K H G H A K
Baker's Yeast Sacchar. cerevisiae P23301 157 17096 T49 V D M S T S K T G K H G H A K
Red Bread Mold Neurospora crassa P38672 163 18017 T55 V D M S T S K T G K H G H A K
Conservation
Percent
Protein Identity: 100 52.7 79.4 N.A. N.A. 39.7 N.A. N.A. N.A. 82.4 81.1 80 N.A. 64.7 66.8 59 63.4
Protein Similarity: 100 52.7 79.4 N.A. N.A. 41.4 N.A. N.A. N.A. 90.2 91.5 90.3 N.A. 80.5 79.3 73.9 77.5
P-Site Identity: 100 93.3 93.3 N.A. N.A. 93.3 N.A. N.A. N.A. 93.3 93.3 93.3 N.A. 93.3 93.3 93.3 93.3
P-Site Similarity: 100 93.3 93.3 N.A. N.A. 93.3 N.A. N.A. N.A. 93.3 93.3 93.3 N.A. 93.3 93.3 93.3 93.3
Percent
Protein Identity: N.A. 51.2 N.A. 53.8 60.5 58.2
Protein Similarity: N.A. 71.2 N.A. 74 80.8 73.6
P-Site Identity: N.A. 86.6 N.A. 86.6 86.6 86.6
P-Site Similarity: N.A. 93.3 N.A. 93.3 93.3 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 0 0 0 0 0 0 100 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 87 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 100 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 100 0 100 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 100 0 0 100 0 0 0 0 100 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 87 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 100 0 100 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 94 0 0 100 0 0 0 0 0 0 0 % T
% Val: 100 0 14 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _