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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF5AL1
All Species:
13.64
Human Site:
Y127
Identified Species:
21.43
UniProt:
Q6IS14
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6IS14
NP_001093162.1
154
16773
Y127
G
K
E
I
E
Q
K
Y
D
C
G
E
E
I
L
Chimpanzee
Pan troglodytes
XP_001174773
286
30517
Y259
G
K
E
I
E
Q
K
Y
D
C
G
E
E
I
L
Rhesus Macaque
Macaca mulatta
XP_001118011
190
21255
Y163
G
K
E
I
E
Q
K
Y
D
C
G
E
E
I
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_001472697
357
39965
Y127
G
K
E
I
E
Q
K
Y
D
C
G
E
E
I
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q07460
153
16702
F127
G
K
E
I
E
G
K
F
N
A
N
E
D
V
Q
Frog
Xenopus laevis
NP_001080536
154
16686
H127
G
K
E
I
L
A
K
H
E
A
G
E
E
I
L
Zebra Danio
Brachydanio rerio
NP_998350
155
16861
F128
G
K
E
I
E
N
K
F
A
A
G
E
E
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GU68
159
17573
F129
G
E
Q
L
R
L
D
F
D
S
G
K
D
L
L
Honey Bee
Apis mellifera
XP_624951
160
17574
H130
G
A
Q
L
R
A
D
H
E
A
G
K
E
L
L
Nematode Worm
Caenorhab. elegans
Q20751
161
17935
E133
Q
Q
I
R
D
A
Y
E
K
D
E
G
S
V
L
Sea Urchin
Strong. purpuratus
XP_785877
156
17276
A129
G
K
E
I
K
K
K
A
E
I
G
E
P
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P80639
160
17478
F132
V
A
Q
I
K
E
G
F
E
S
G
K
D
L
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI91
158
17342
F130
L
Q
Q
I
K
S
G
F
D
D
G
K
D
L
V
Baker's Yeast
Sacchar. cerevisiae
P23301
157
17096
F128
G
D
S
L
Q
T
A
F
D
E
G
K
D
L
M
Red Bread Mold
Neurospora crassa
P38672
163
18017
E134
A
K
R
I
E
K
L
E
E
E
G
K
D
F
F
Conservation
Percent
Protein Identity:
100
52.7
79.4
N.A.
N.A.
39.7
N.A.
N.A.
N.A.
82.4
81.1
80
N.A.
64.7
66.8
59
63.4
Protein Similarity:
100
52.7
79.4
N.A.
N.A.
41.4
N.A.
N.A.
N.A.
90.2
91.5
90.3
N.A.
80.5
79.3
73.9
77.5
P-Site Identity:
100
100
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
46.6
66.6
66.6
N.A.
26.6
26.6
6.6
46.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
73.3
80
80
N.A.
73.3
66.6
26.6
66.6
Percent
Protein Identity:
N.A.
51.2
N.A.
53.8
60.5
58.2
Protein Similarity:
N.A.
71.2
N.A.
74
80.8
73.6
P-Site Identity:
N.A.
13.3
N.A.
20
20
26.6
P-Site Similarity:
N.A.
73.3
N.A.
73.3
66.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
0
0
0
20
7
7
7
27
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
27
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
0
14
0
47
14
0
0
40
0
0
% D
% Glu:
0
7
54
0
47
7
0
14
34
14
7
54
47
0
0
% E
% Phe:
0
0
0
0
0
0
0
40
0
0
0
0
0
14
7
% F
% Gly:
74
0
0
0
0
7
14
0
0
0
87
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
74
0
0
0
0
0
7
0
0
0
34
0
% I
% Lys:
0
60
0
0
20
14
54
0
7
0
0
40
0
0
0
% K
% Leu:
7
0
0
20
7
7
7
0
0
0
0
0
0
34
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
0
0
0
7
0
0
7
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
7
14
27
0
7
27
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
7
7
14
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
0
7
0
0
0
14
0
0
7
0
0
% S
% Thr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
0
0
0
14
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
27
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _