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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WBSCR17 All Species: 33.33
Human Site: S125 Identified Species: 73.33
UniProt: Q6IS24 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6IS24 NP_071924.1 598 67751 S125 Y G Y N S Y L S E K I S L D R
Chimpanzee Pan troglodytes XP_001142210 598 67760 S125 Y G Y N S Y L S E K I S L D R
Rhesus Macaque Macaca mulatta XP_001106039 597 67318 S124 Y G Y N A Q L S D R I S L D R
Dog Lupus familis XP_848526 598 67676 S125 Y G Y N S Y L S E K I S L D R
Cat Felis silvestris
Mouse Mus musculus Q7TT15 598 67673 S125 Y G Y N S Y L S E K I S L D R
Rat Rattus norvegicus Q6UE39 556 63930 T107 V R L E G C K T K V Y P D E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508458 303 34297
Chicken Gallus gallus XP_415728 598 67826 S125 Y G Y N S Y L S E K I S L D R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696189 617 70377 S127 Y G Y N A F L S D K I S L D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q6WV17 630 72079 S160 N Q F N L L A S D M I S L N R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95ZJ1 626 71364 S148 N A F N Q Y A S D M I S V H R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 59.2 98.8 N.A. 98.4 35.4 N.A. 34.7 94.9 N.A. 69.5 N.A. 33.1 N.A. 33.3 N.A.
Protein Similarity: 100 100 76.2 99.5 N.A. 99.3 55 N.A. 43.4 96.9 N.A. 80.7 N.A. 52.2 N.A. 52 N.A.
P-Site Identity: 100 100 73.3 100 N.A. 100 0 N.A. 0 100 N.A. 80 N.A. 40 N.A. 40 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 100 20 N.A. 0 100 N.A. 100 N.A. 60 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 19 0 19 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 37 0 0 0 10 64 0 % D
% Glu: 0 0 0 10 0 0 0 0 46 0 0 0 0 10 0 % E
% Phe: 0 0 19 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 64 0 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 82 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 10 55 0 0 0 0 0 % K
% Leu: 0 0 10 0 10 10 64 0 0 0 0 0 73 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % M
% Asn: 19 0 0 82 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 10 0 0 10 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 82 % R
% Ser: 0 0 0 0 46 0 0 82 0 0 0 82 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 64 0 64 0 0 55 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _