Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC24A6 All Species: 10
Human Site: S258 Identified Species: 18.33
UniProt: Q6J4K2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6J4K2 NP_079235.2 584 64231 S258 Y Q R Q R R G S L F C P M P V
Chimpanzee Pan troglodytes XP_001152666 584 64322 S258 Y R R Q R R G S L F C P M P V
Rhesus Macaque Macaca mulatta XP_001104394 268 29214
Dog Lupus familis XP_543406 395 43491 L100 G R A G A P A L L L C V P L T
Cat Felis silvestris
Mouse Mus musculus Q925Q3 585 64346 S258 Y Q R Q R S R S L V H S I S E
Rat Rattus norvegicus Q6AXS0 585 63974 S258 Y Q R Q R S R S L V H S I S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9IAL7 651 72677 E302 V L N R N K V E K A T T G D A
Frog Xenopus laevis NP_001128697 548 61016 G252 T P H G S E Y G D E Y Q P L F
Zebra Danio Brachydanio rerio Q49SH1 513 56764 V218 D G A C L L L V Y G V Y V A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN12 642 70657 N284 E R W A L G L N L P F K L P S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34315 590 66151 E261 H N R H K K D E E K V D E V K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002304130 506 54291 T211 S S L L D L E T E S D V P H L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LJI2 643 70138 K299 R K H A K R F K L E A L T P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 43.6 48.6 N.A. 82.7 82.7 N.A. N.A. 22.8 60.9 23.1 N.A. 22.1 N.A. 30.1 N.A.
Protein Similarity: 100 99.6 44.8 53.5 N.A. 88.3 89 N.A. N.A. 42.4 74.1 42.1 N.A. 40.5 N.A. 50.8 N.A.
P-Site Identity: 100 93.3 0 13.3 N.A. 46.6 46.6 N.A. N.A. 0 0 6.6 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 0 20 N.A. 53.3 53.3 N.A. N.A. 13.3 0 13.3 N.A. 33.3 N.A. 26.6 N.A.
Percent
Protein Identity: 26.8 N.A. N.A. 27.8 N.A. N.A.
Protein Similarity: 47.6 N.A. N.A. 47.7 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 16 8 0 8 0 0 8 8 0 0 8 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 24 0 0 0 0 % C
% Asp: 8 0 0 0 8 0 8 0 8 0 8 8 0 8 0 % D
% Glu: 8 0 0 0 0 8 8 16 16 16 0 0 8 0 16 % E
% Phe: 0 0 0 0 0 0 8 0 0 16 8 0 0 0 8 % F
% Gly: 8 8 0 16 0 8 16 8 0 8 0 0 8 0 0 % G
% His: 8 0 16 8 0 0 0 0 0 0 16 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % I
% Lys: 0 8 0 0 16 16 0 8 8 8 0 8 0 0 8 % K
% Leu: 0 8 8 8 16 16 16 8 54 8 0 8 8 16 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % M
% Asn: 0 8 8 0 8 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 8 0 0 0 8 0 16 24 31 0 % P
% Gln: 0 24 0 31 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 8 24 39 8 31 24 16 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 0 0 8 16 0 31 0 8 0 16 0 16 8 % S
% Thr: 8 0 0 0 0 0 0 8 0 0 8 8 8 0 8 % T
% Val: 8 0 0 0 0 0 8 8 0 16 16 16 8 8 24 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 31 0 0 0 0 0 8 0 8 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _