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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A6
All Species:
10
Human Site:
S258
Identified Species:
18.33
UniProt:
Q6J4K2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6J4K2
NP_079235.2
584
64231
S258
Y
Q
R
Q
R
R
G
S
L
F
C
P
M
P
V
Chimpanzee
Pan troglodytes
XP_001152666
584
64322
S258
Y
R
R
Q
R
R
G
S
L
F
C
P
M
P
V
Rhesus Macaque
Macaca mulatta
XP_001104394
268
29214
Dog
Lupus familis
XP_543406
395
43491
L100
G
R
A
G
A
P
A
L
L
L
C
V
P
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q925Q3
585
64346
S258
Y
Q
R
Q
R
S
R
S
L
V
H
S
I
S
E
Rat
Rattus norvegicus
Q6AXS0
585
63974
S258
Y
Q
R
Q
R
S
R
S
L
V
H
S
I
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IAL7
651
72677
E302
V
L
N
R
N
K
V
E
K
A
T
T
G
D
A
Frog
Xenopus laevis
NP_001128697
548
61016
G252
T
P
H
G
S
E
Y
G
D
E
Y
Q
P
L
F
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
V218
D
G
A
C
L
L
L
V
Y
G
V
Y
V
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN12
642
70657
N284
E
R
W
A
L
G
L
N
L
P
F
K
L
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34315
590
66151
E261
H
N
R
H
K
K
D
E
E
K
V
D
E
V
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002304130
506
54291
T211
S
S
L
L
D
L
E
T
E
S
D
V
P
H
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LJI2
643
70138
K299
R
K
H
A
K
R
F
K
L
E
A
L
T
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
43.6
48.6
N.A.
82.7
82.7
N.A.
N.A.
22.8
60.9
23.1
N.A.
22.1
N.A.
30.1
N.A.
Protein Similarity:
100
99.6
44.8
53.5
N.A.
88.3
89
N.A.
N.A.
42.4
74.1
42.1
N.A.
40.5
N.A.
50.8
N.A.
P-Site Identity:
100
93.3
0
13.3
N.A.
46.6
46.6
N.A.
N.A.
0
0
6.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
0
20
N.A.
53.3
53.3
N.A.
N.A.
13.3
0
13.3
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
26.8
N.A.
N.A.
27.8
N.A.
N.A.
Protein Similarity:
47.6
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
16
8
0
8
0
0
8
8
0
0
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
24
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
8
0
8
0
8
8
0
8
0
% D
% Glu:
8
0
0
0
0
8
8
16
16
16
0
0
8
0
16
% E
% Phe:
0
0
0
0
0
0
8
0
0
16
8
0
0
0
8
% F
% Gly:
8
8
0
16
0
8
16
8
0
8
0
0
8
0
0
% G
% His:
8
0
16
8
0
0
0
0
0
0
16
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% I
% Lys:
0
8
0
0
16
16
0
8
8
8
0
8
0
0
8
% K
% Leu:
0
8
8
8
16
16
16
8
54
8
0
8
8
16
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
8
8
0
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
8
0
16
24
31
0
% P
% Gln:
0
24
0
31
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
24
39
8
31
24
16
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
8
16
0
31
0
8
0
16
0
16
8
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
8
8
8
0
8
% T
% Val:
8
0
0
0
0
0
8
8
0
16
16
16
8
8
24
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
31
0
0
0
0
0
8
0
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _