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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A6
All Species:
19.09
Human Site:
S271
Identified Species:
35
UniProt:
Q6J4K2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6J4K2
NP_079235.2
584
64231
S271
P
V
T
P
E
I
L
S
D
S
E
E
D
R
V
Chimpanzee
Pan troglodytes
XP_001152666
584
64322
S271
P
V
T
P
E
I
L
S
D
S
E
E
D
R
V
Rhesus Macaque
Macaca mulatta
XP_001104394
268
29214
Dog
Lupus familis
XP_543406
395
43491
V113
L
T
C
S
P
H
G
V
T
F
L
A
F
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q925Q3
585
64346
S271
S
E
T
P
E
L
L
S
E
S
E
E
D
Q
M
Rat
Rattus norvegicus
Q6AXS0
585
63974
T271
S
E
T
P
E
L
L
T
D
S
E
E
D
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IAL7
651
72677
T315
D
A
E
G
K
S
P
T
A
G
D
K
D
D
Q
Frog
Xenopus laevis
NP_001128697
548
61016
T265
L
F
P
M
Q
R
S
T
W
Q
I
L
T
S
E
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
R231
A
V
L
C
F
D
L
R
I
S
E
Y
V
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN12
642
70657
A297
P
S
K
E
E
Q
S
A
L
V
T
Y
K
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34315
590
66151
S274
V
K
T
V
D
T
D
S
L
E
D
D
D
D
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002304130
506
54291
S224
H
L
P
S
S
L
P
S
W
M
W
A
S
N
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LJI2
643
70138
S312
P
L
L
P
M
Q
G
S
V
F
S
P
S
V
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
43.6
48.6
N.A.
82.7
82.7
N.A.
N.A.
22.8
60.9
23.1
N.A.
22.1
N.A.
30.1
N.A.
Protein Similarity:
100
99.6
44.8
53.5
N.A.
88.3
89
N.A.
N.A.
42.4
74.1
42.1
N.A.
40.5
N.A.
50.8
N.A.
P-Site Identity:
100
100
0
0
N.A.
60
60
N.A.
N.A.
6.6
0
26.6
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
100
0
0
N.A.
86.6
86.6
N.A.
N.A.
33.3
13.3
26.6
N.A.
26.6
N.A.
46.6
N.A.
Percent
Protein Identity:
26.8
N.A.
N.A.
27.8
N.A.
N.A.
Protein Similarity:
47.6
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
8
0
0
16
0
0
0
% A
% Cys:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
8
0
24
0
16
8
47
16
0
% D
% Glu:
0
16
8
8
39
0
0
0
8
8
39
31
0
0
8
% E
% Phe:
0
8
0
0
8
0
0
0
0
16
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
16
0
0
8
0
0
0
8
8
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
8
0
8
0
0
0
8
% I
% Lys:
0
8
8
0
8
0
0
0
0
0
0
8
8
0
0
% K
% Leu:
16
16
16
0
0
24
39
0
16
0
8
8
0
0
0
% L
% Met:
0
0
0
8
8
0
0
0
0
8
0
0
0
8
16
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% N
% Pro:
31
0
16
39
8
0
16
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
16
0
0
0
8
0
0
0
16
16
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
0
0
0
16
0
% R
% Ser:
16
8
0
16
8
8
16
47
0
39
8
0
16
8
0
% S
% Thr:
0
8
39
0
0
8
0
24
8
0
8
0
8
0
0
% T
% Val:
8
24
0
8
0
0
0
8
8
8
0
0
8
8
31
% V
% Trp:
0
0
0
0
0
0
0
0
16
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _