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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A6
All Species:
14.55
Human Site:
S273
Identified Species:
26.67
UniProt:
Q6J4K2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6J4K2
NP_079235.2
584
64231
S273
T
P
E
I
L
S
D
S
E
E
D
R
V
S
S
Chimpanzee
Pan troglodytes
XP_001152666
584
64322
S273
T
P
E
I
L
S
D
S
E
E
D
R
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001104394
268
29214
Dog
Lupus familis
XP_543406
395
43491
F115
C
S
P
H
G
V
T
F
L
A
F
G
N
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q925Q3
585
64346
S273
T
P
E
L
L
S
E
S
E
E
D
Q
M
S
S
Rat
Rattus norvegicus
Q6AXS0
585
63974
S273
T
P
E
L
L
T
D
S
E
E
D
Q
M
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IAL7
651
72677
G317
E
G
K
S
P
T
A
G
D
K
D
D
Q
T
L
Frog
Xenopus laevis
NP_001128697
548
61016
Q267
P
M
Q
R
S
T
W
Q
I
L
T
S
E
L
N
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
S233
L
C
F
D
L
R
I
S
E
Y
V
M
Q
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN12
642
70657
V299
K
E
E
Q
S
A
L
V
T
Y
K
N
V
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34315
590
66151
E276
T
V
D
T
D
S
L
E
D
D
D
D
I
Y
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002304130
506
54291
M226
P
S
S
L
P
S
W
M
W
A
S
N
V
A
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LJI2
643
70138
F314
L
P
M
Q
G
S
V
F
S
P
S
V
G
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
43.6
48.6
N.A.
82.7
82.7
N.A.
N.A.
22.8
60.9
23.1
N.A.
22.1
N.A.
30.1
N.A.
Protein Similarity:
100
99.6
44.8
53.5
N.A.
88.3
89
N.A.
N.A.
42.4
74.1
42.1
N.A.
40.5
N.A.
50.8
N.A.
P-Site Identity:
100
100
0
0
N.A.
73.3
73.3
N.A.
N.A.
6.6
0
20
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
100
0
6.6
N.A.
100
100
N.A.
N.A.
40
20
20
N.A.
20
N.A.
46.6
N.A.
Percent
Protein Identity:
26.8
N.A.
N.A.
27.8
N.A.
N.A.
Protein Similarity:
47.6
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
0
16
0
0
0
8
8
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
8
0
24
0
16
8
47
16
0
0
8
% D
% Glu:
8
8
39
0
0
0
8
8
39
31
0
0
8
8
8
% E
% Phe:
0
0
8
0
0
0
0
16
0
0
8
0
0
0
8
% F
% Gly:
0
8
0
0
16
0
0
8
0
0
0
8
8
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
8
0
8
0
0
0
8
0
8
% I
% Lys:
8
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% K
% Leu:
16
0
0
24
39
0
16
0
8
8
0
0
0
8
8
% L
% Met:
0
8
8
0
0
0
0
8
0
0
0
8
16
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
16
8
0
8
% N
% Pro:
16
39
8
0
16
0
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
8
16
0
0
0
8
0
0
0
16
16
0
0
% Q
% Arg:
0
0
0
8
0
8
0
0
0
0
0
16
0
8
0
% R
% Ser:
0
16
8
8
16
47
0
39
8
0
16
8
0
31
31
% S
% Thr:
39
0
0
8
0
24
8
0
8
0
8
0
0
8
0
% T
% Val:
0
8
0
0
0
8
8
8
0
0
8
8
31
0
8
% V
% Trp:
0
0
0
0
0
0
16
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
16
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _