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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL10
All Species:
17.88
Human Site:
S212
Identified Species:
32.78
UniProt:
Q6JEL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6JEL2
NP_689680.2
608
68942
S212
E
A
I
L
K
W
I
S
H
D
P
Q
N
R
K
Chimpanzee
Pan troglodytes
XP_001167701
608
68899
S212
E
A
I
L
K
W
I
S
H
D
P
Q
N
R
K
Rhesus Macaque
Macaca mulatta
XP_001093757
555
62750
I169
P
Q
N
R
K
Q
H
I
S
I
L
L
P
K
V
Dog
Lupus familis
XP_537641
608
68948
S212
E
A
I
L
K
W
I
S
H
D
S
Q
N
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V2
608
68958
S212
E
A
I
L
K
W
I
S
H
D
P
Q
N
R
K
Rat
Rattus norvegicus
Q6JEL3
608
68944
S212
E
A
I
L
K
W
I
S
H
D
P
Q
N
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
F305
L
L
R
I
A
D
K
F
T
Q
H
N
F
Q
E
Chicken
Gallus gallus
XP_418155
584
66006
E198
D
E
L
N
V
K
Q
E
E
V
V
F
D
A
I
Frog
Xenopus laevis
Q6NRH0
564
63190
V175
M
L
L
H
Q
E
E
V
E
K
L
I
H
C
D
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
V175
M
L
L
S
Q
S
E
V
E
K
L
I
K
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
F236
V
R
S
E
E
Q
V
F
N
A
V
M
S
W
L
Honey Bee
Apis mellifera
XP_395435
661
75679
D225
V
L
K
W
I
D
Y
D
P
Q
S
R
K
D
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796178
830
95048
V202
F
E
A
L
V
R
W
V
R
H
K
E
T
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
98.6
N.A.
98.8
98.8
N.A.
22.1
77.3
32.2
31.9
N.A.
35.3
47.2
N.A.
37.5
Protein Similarity:
100
99.8
90.3
99
N.A.
99.1
99.3
N.A.
39.6
85.1
50.3
50.1
N.A.
52.9
65.3
N.A.
51
P-Site Identity:
100
100
6.6
93.3
N.A.
100
100
N.A.
0
0
0
0
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
20
20
20
13.3
N.A.
26.6
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
8
0
8
0
0
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% C
% Asp:
8
0
0
0
0
16
0
8
0
39
0
0
8
8
16
% D
% Glu:
39
16
0
8
8
8
16
8
24
0
0
8
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
16
0
0
0
8
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
8
0
39
8
8
0
8
0
0
% H
% Ile:
0
0
39
8
8
0
39
8
0
8
0
16
0
0
8
% I
% Lys:
0
0
8
0
47
8
8
0
0
16
8
0
16
8
39
% K
% Leu:
8
31
24
47
0
0
0
0
0
0
24
8
0
0
8
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
8
0
0
8
39
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
31
0
8
0
0
% P
% Gln:
0
8
0
0
16
16
8
0
0
16
0
39
0
16
0
% Q
% Arg:
0
8
8
8
0
8
0
0
8
0
0
8
0
39
8
% R
% Ser:
0
0
8
8
0
8
0
39
8
0
16
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% T
% Val:
16
0
0
0
16
0
8
24
0
8
16
0
0
0
8
% V
% Trp:
0
0
0
8
0
39
8
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _