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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL10
All Species:
24.85
Human Site:
S380
Identified Species:
45.56
UniProt:
Q6JEL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6JEL2
NP_689680.2
608
68942
S380
H
S
R
R
C
Y
V
S
V
T
V
L
G
N
F
Chimpanzee
Pan troglodytes
XP_001167701
608
68899
S380
H
S
R
R
C
Y
V
S
V
T
V
L
G
N
F
Rhesus Macaque
Macaca mulatta
XP_001093757
555
62750
A337
V
L
S
N
F
I
Y
A
M
G
G
F
D
G
Y
Dog
Lupus familis
XP_537641
608
68948
S380
H
S
R
R
C
Y
V
S
V
T
V
L
S
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V2
608
68958
S380
H
S
R
R
C
Y
V
S
V
T
V
L
S
N
F
Rat
Rattus norvegicus
Q6JEL3
608
68944
S380
H
S
R
R
C
Y
V
S
V
T
V
L
S
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
V473
K
R
R
C
G
V
G
V
S
V
L
D
D
L
L
Chicken
Gallus gallus
XP_418155
584
66006
Q366
P
V
K
K
T
W
H
Q
V
A
P
M
H
S
R
Frog
Xenopus laevis
Q6NRH0
564
63190
E343
R
S
R
L
S
S
V
E
C
L
D
Y
T
S
E
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
E343
R
S
R
L
S
S
V
E
C
L
D
Y
T
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
T404
S
C
D
V
A
P
T
T
S
C
R
T
S
V
G
Honey Bee
Apis mellifera
XP_395435
661
75679
S393
N
A
R
R
C
Y
V
S
V
A
V
L
N
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796178
830
95048
S370
N
S
R
R
C
Y
V
S
V
S
T
L
G
E
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
98.6
N.A.
98.8
98.8
N.A.
22.1
77.3
32.2
31.9
N.A.
35.3
47.2
N.A.
37.5
Protein Similarity:
100
99.8
90.3
99
N.A.
99.1
99.3
N.A.
39.6
85.1
50.3
50.1
N.A.
52.9
65.3
N.A.
51
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
6.6
6.6
20
20
N.A.
0
60
N.A.
66.6
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
13.3
40
26.6
20
N.A.
6.6
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
8
0
16
0
0
0
8
0
% A
% Cys:
0
8
0
8
54
0
0
0
16
8
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
16
8
16
8
8
% D
% Glu:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
39
% F
% Gly:
0
0
0
0
8
0
8
0
0
8
8
0
24
8
8
% G
% His:
39
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
16
0
0
0
0
0
16
8
54
0
8
16
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
16
0
0
8
0
0
0
0
0
0
0
0
8
39
0
% N
% Pro:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
16
8
77
54
0
0
0
0
0
0
8
0
0
0
8
% R
% Ser:
8
62
8
0
16
16
0
54
16
8
0
0
31
16
0
% S
% Thr:
0
0
0
0
8
0
8
8
0
39
8
8
16
0
0
% T
% Val:
8
8
0
8
0
8
70
8
62
8
47
0
0
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
54
8
0
0
0
0
16
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _