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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL10 All Species: 18.18
Human Site: S501 Identified Species: 33.33
UniProt: Q6JEL2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6JEL2 NP_689680.2 608 68942 S501 L R S A E A Y S P V A N T W R
Chimpanzee Pan troglodytes XP_001167701 608 68899 S501 L R S A E A Y S P V A N T W R
Rhesus Macaque Macaca mulatta XP_001093757 555 62750 P458 A N T W R T I P T M F N P R S
Dog Lupus familis XP_537641 608 68948 S501 L R S A E A Y S P V A N T W R
Cat Felis silvestris
Mouse Mus musculus Q9D5V2 608 68958 S501 L R S A E A Y S P V A N T W R
Rat Rattus norvegicus Q6JEL3 608 68944 S501 L R S A E A Y S P V A N T W R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515196 722 79884 N594 L N T V E R Y N P Q E N R W H
Chicken Gallus gallus XP_418155 584 66006 D487 V Y A V G G F D G V N R L R T
Frog Xenopus laevis Q6NRH0 564 63190 V464 T K R S G A G V S L L N D H I
Zebra Danio Brachydanio rerio Q5U374 564 62914 V464 N K R S G A G V A L L N D H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 L525 G R D D C M E L S S A E R Y N
Honey Bee Apis mellifera XP_395435 661 75679 N514 M C S G E K Y N P A T D V W T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796178 830 95048 K491 L N S M E R W K P G T M Q W I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 90.1 98.6 N.A. 98.8 98.8 N.A. 22.1 77.3 32.2 31.9 N.A. 35.3 47.2 N.A. 37.5
Protein Similarity: 100 99.8 90.3 99 N.A. 99.1 99.3 N.A. 39.6 85.1 50.3 50.1 N.A. 52.9 65.3 N.A. 51
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 40 6.6 13.3 13.3 N.A. 13.3 33.3 N.A. 33.3
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 53.3 26.6 33.3 33.3 N.A. 20 53.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 39 0 54 0 0 8 8 47 0 0 0 0 % A
% Cys: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 0 8 0 0 0 8 16 0 0 % D
% Glu: 0 0 0 0 62 0 8 0 0 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 8 24 8 16 0 8 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 8 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 24 % I
% Lys: 0 16 0 0 0 8 0 8 0 0 0 0 0 0 0 % K
% Leu: 54 0 0 0 0 0 0 8 0 16 16 0 8 0 0 % L
% Met: 8 0 0 8 0 8 0 0 0 8 0 8 0 0 0 % M
% Asn: 8 24 0 0 0 0 0 16 0 0 8 70 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 8 62 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % Q
% Arg: 0 47 16 0 8 16 0 0 0 0 0 8 16 16 39 % R
% Ser: 0 0 54 16 0 0 0 39 16 8 0 0 0 0 8 % S
% Thr: 8 0 16 0 0 8 0 0 8 0 16 0 39 0 16 % T
% Val: 8 0 0 16 0 0 0 16 0 47 0 0 8 0 0 % V
% Trp: 0 0 0 8 0 0 8 0 0 0 0 0 0 62 0 % W
% Tyr: 0 8 0 0 0 0 54 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _