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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL10
All Species:
26.36
Human Site:
S518
Identified Species:
48.33
UniProt:
Q6JEL2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6JEL2
NP_689680.2
608
68942
S518
P
T
M
F
N
P
R
S
N
F
G
I
E
V
V
Chimpanzee
Pan troglodytes
XP_001167701
608
68899
S518
P
T
M
F
N
P
R
S
N
F
G
I
E
V
V
Rhesus Macaque
Macaca mulatta
XP_001093757
555
62750
L475
G
I
E
V
V
D
D
L
L
F
V
V
G
G
F
Dog
Lupus familis
XP_537641
608
68948
S518
P
T
M
F
N
P
R
S
N
F
G
I
E
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V2
608
68958
S518
P
T
M
F
N
P
R
S
N
F
G
I
E
V
V
Rat
Rattus norvegicus
Q6JEL3
608
68944
S518
P
T
M
F
N
P
R
S
N
F
G
I
E
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
K611
A
P
M
G
T
R
R
K
H
L
G
C
A
V
Y
Chicken
Gallus gallus
XP_418155
584
66006
T504
A
Y
N
P
A
A
N
T
W
R
V
V
P
T
M
Frog
Xenopus laevis
Q6NRH0
564
63190
A481
V
G
G
F
D
G
T
A
H
L
S
S
V
E
A
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
A481
V
G
G
F
D
G
T
A
H
L
S
S
V
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
V542
T
N
T
W
S
P
I
V
A
M
T
S
R
R
S
Honey Bee
Apis mellifera
XP_395435
661
75679
S531
P
D
M
Y
N
S
R
S
N
F
A
I
E
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796178
830
95048
S508
P
S
M
Y
I
H
R
S
N
F
G
V
A
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
98.6
N.A.
98.8
98.8
N.A.
22.1
77.3
32.2
31.9
N.A.
35.3
47.2
N.A.
37.5
Protein Similarity:
100
99.8
90.3
99
N.A.
99.1
99.3
N.A.
39.6
85.1
50.3
50.1
N.A.
52.9
65.3
N.A.
51
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
26.6
0
6.6
13.3
N.A.
6.6
66.6
N.A.
53.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
33.3
20
26.6
33.3
N.A.
20
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
8
8
0
16
8
0
8
0
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
16
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
47
16
0
% E
% Phe:
0
0
0
54
0
0
0
0
0
62
0
0
0
0
8
% F
% Gly:
8
16
16
8
0
16
0
0
0
0
54
0
8
8
0
% G
% His:
0
0
0
0
0
8
0
0
24
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
8
0
0
0
0
47
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
24
0
0
0
0
8
% L
% Met:
0
0
62
0
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
8
8
0
47
0
8
0
54
0
0
0
0
0
0
% N
% Pro:
54
8
0
8
0
47
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
62
0
0
8
0
0
8
8
0
% R
% Ser:
0
8
0
0
8
8
0
54
0
0
16
24
0
0
8
% S
% Thr:
8
39
8
0
8
0
16
8
0
0
8
0
0
8
0
% T
% Val:
16
0
0
8
8
0
0
8
0
0
16
24
16
62
47
% V
% Trp:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _