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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL10 All Species: 27.58
Human Site: T461 Identified Species: 50.56
UniProt: Q6JEL2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6JEL2 NP_689680.2 608 68942 T461 N T E S N Q W T V I A P M R S
Chimpanzee Pan troglodytes XP_001167701 608 68899 T461 N T E S N Q W T V I A P M R S
Rhesus Macaque Macaca mulatta XP_001093757 555 62750 S418 A P M R S R R S G I G V I A Y
Dog Lupus familis XP_537641 608 68948 T461 N T E S N Q W T V I A P M R S
Cat Felis silvestris
Mouse Mus musculus Q9D5V2 608 68958 T461 N T E S N Q W T V I A P M R S
Rat Rattus norvegicus Q6JEL3 608 68944 T461 N T E S N Q W T V I A P M R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515196 722 79884 T554 D P K E N K W T R V A S M S T
Chicken Gallus gallus XP_418155 584 66006 T447 N G N E C L S T A E V Y D A G
Frog Xenopus laevis Q6NRH0 564 63190 I424 L V V A N G V I Y C L G G Y D
Zebra Danio Brachydanio rerio Q5U374 564 62914 I424 L V V A S G L I Y C L G G Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 D485 L N T V E R Y D P R H N K W V
Honey Bee Apis mellifera XP_395435 661 75679 T474 D P E T N Q W T I I A P M R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796178 830 95048 R451 D P E L D E W R D I P R M N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 90.1 98.6 N.A. 98.8 98.8 N.A. 22.1 77.3 32.2 31.9 N.A. 35.3 47.2 N.A. 37.5
Protein Similarity: 100 99.8 90.3 99 N.A. 99.1 99.3 N.A. 39.6 85.1 50.3 50.1 N.A. 52.9 65.3 N.A. 51
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 33.3 13.3 6.6 0 N.A. 0 73.3 N.A. 33.3
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. 66.6 13.3 13.3 13.3 N.A. 13.3 93.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 16 0 0 0 0 8 0 54 0 0 16 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 16 0 0 0 0 0 % C
% Asp: 24 0 0 0 8 0 0 8 8 0 0 0 8 0 16 % D
% Glu: 0 0 54 16 8 8 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 16 0 0 8 0 8 16 16 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 16 8 62 0 0 8 0 0 % I
% Lys: 0 0 8 0 0 8 0 0 0 0 0 0 8 0 0 % K
% Leu: 24 0 0 8 0 8 8 0 0 0 16 0 0 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 62 0 0 % M
% Asn: 47 8 8 0 62 0 0 0 0 0 0 8 0 8 0 % N
% Pro: 0 31 0 0 0 0 0 0 8 0 8 47 0 0 0 % P
% Gln: 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 16 8 8 8 8 0 8 0 47 0 % R
% Ser: 0 0 0 39 16 0 8 8 0 0 0 8 0 8 54 % S
% Thr: 0 39 8 8 0 0 0 62 0 0 0 0 0 0 8 % T
% Val: 0 16 16 8 0 0 8 0 39 8 8 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 62 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 8 0 16 0 0 8 0 16 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _