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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL10
All Species:
20.91
Human Site:
Y152
Identified Species:
38.33
UniProt:
Q6JEL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6JEL2
NP_689680.2
608
68942
Y152
C
K
F
T
D
Y
Y
Y
C
P
E
L
R
Q
K
Chimpanzee
Pan troglodytes
XP_001167701
608
68899
Y152
C
K
F
T
D
Y
Y
Y
C
P
E
L
R
Q
K
Rhesus Macaque
Macaca mulatta
XP_001093757
555
62750
S122
F
E
E
M
V
K
V
S
A
E
F
L
E
L
S
Dog
Lupus familis
XP_537641
608
68948
Y152
C
K
F
T
D
Y
Y
Y
C
P
E
L
R
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V2
608
68958
Y152
C
K
F
T
D
Y
Y
Y
C
P
E
L
R
Q
K
Rat
Rattus norvegicus
Q6JEL3
608
68944
Y152
C
K
F
T
D
Y
Y
Y
C
P
E
L
R
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
G212
Y
F
R
A
M
F
T
G
E
L
A
E
S
R
Q
Chicken
Gallus gallus
XP_418155
584
66006
H150
C
R
L
T
N
Y
Y
H
C
P
G
L
R
Q
T
Frog
Xenopus laevis
Q6NRH0
564
63190
P128
F
L
E
S
Q
L
D
P
S
N
C
L
G
I
R
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
P128
F
L
N
S
Q
L
D
P
S
N
C
L
G
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
S185
R
A
F
A
D
T
H
S
C
R
E
L
L
R
I
Honey Bee
Apis mellifera
XP_395435
661
75679
F163
M
R
F
A
R
E
H
F
C
K
G
L
E
N
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796178
830
95048
F141
W
R
F
A
R
S
Y
F
C
F
L
L
E
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
98.6
N.A.
98.8
98.8
N.A.
22.1
77.3
32.2
31.9
N.A.
35.3
47.2
N.A.
37.5
Protein Similarity:
100
99.8
90.3
99
N.A.
99.1
99.3
N.A.
39.6
85.1
50.3
50.1
N.A.
52.9
65.3
N.A.
51
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
0
60
6.6
6.6
N.A.
33.3
20
N.A.
33.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
20
80
20
20
N.A.
46.6
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
31
0
0
0
0
8
0
8
0
0
0
0
% A
% Cys:
47
0
0
0
0
0
0
0
70
0
16
0
0
0
0
% C
% Asp:
0
0
0
0
47
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
16
0
0
8
0
0
8
8
47
8
24
0
0
% E
% Phe:
24
8
62
0
0
8
0
16
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
16
0
16
0
0
% G
% His:
0
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% I
% Lys:
0
39
0
0
0
8
0
0
0
8
0
0
0
0
39
% K
% Leu:
0
16
8
0
0
16
0
0
0
8
8
93
8
8
0
% L
% Met:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
16
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
16
0
47
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
0
0
0
0
54
8
% Q
% Arg:
8
24
8
0
16
0
0
0
0
8
0
0
47
16
16
% R
% Ser:
0
0
0
16
0
8
0
16
16
0
0
0
8
0
24
% S
% Thr:
0
0
0
47
0
8
8
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
47
54
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _