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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL10
All Species:
18.79
Human Site:
Y248
Identified Species:
34.44
UniProt:
Q6JEL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6JEL2
NP_689680.2
608
68942
Y248
N
N
V
K
M
N
D
Y
V
K
D
S
E
E
C
Chimpanzee
Pan troglodytes
XP_001167701
608
68899
Y248
N
N
V
K
M
N
D
Y
V
K
D
S
E
E
C
Rhesus Macaque
Macaca mulatta
XP_001093757
555
62750
V205
D
S
E
E
C
K
P
V
I
I
N
A
L
K
A
Dog
Lupus familis
XP_537641
608
68948
Y248
N
N
V
K
M
N
D
Y
V
K
D
S
E
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V2
608
68958
Y248
N
N
V
K
M
N
D
Y
V
K
D
S
E
E
C
Rat
Rattus norvegicus
Q6JEL3
608
68944
Y248
N
N
V
K
M
N
D
Y
V
K
D
S
E
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
E341
D
E
L
N
V
R
S
E
E
Q
V
F
N
A
V
Chicken
Gallus gallus
XP_418155
584
66006
A234
V
R
L
A
L
M
E
A
D
H
F
M
N
K
V
Frog
Xenopus laevis
Q6NRH0
564
63190
L211
R
H
E
R
E
K
S
L
P
Q
L
L
Q
Y
V
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
L211
R
K
E
R
E
P
Y
L
P
D
L
L
E
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
V272
L
L
S
P
K
F
L
V
G
T
V
G
S
D
L
Honey Bee
Apis mellifera
XP_395435
661
75679
T261
V
K
D
H
P
Y
V
T
G
N
E
A
C
R
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796178
830
95048
P238
M
N
S
I
K
A
H
P
L
V
R
D
V
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
98.6
N.A.
98.8
98.8
N.A.
22.1
77.3
32.2
31.9
N.A.
35.3
47.2
N.A.
37.5
Protein Similarity:
100
99.8
90.3
99
N.A.
99.1
99.3
N.A.
39.6
85.1
50.3
50.1
N.A.
52.9
65.3
N.A.
51
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
0
0
6.6
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
46.6
100
N.A.
100
100
N.A.
26.6
26.6
26.6
13.3
N.A.
6.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
8
0
0
0
16
0
8
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
39
% C
% Asp:
16
0
8
0
0
0
39
0
8
8
39
8
0
8
0
% D
% Glu:
0
8
24
8
16
0
8
8
8
0
8
0
47
47
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
16
0
0
8
0
0
0
% G
% His:
0
8
0
8
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
16
0
39
16
16
0
0
0
39
0
0
0
16
0
% K
% Leu:
8
8
16
0
8
0
8
16
8
0
16
16
8
0
8
% L
% Met:
8
0
0
0
39
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
39
47
0
8
0
39
0
0
0
8
8
0
16
0
0
% N
% Pro:
0
0
0
8
8
8
8
8
16
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
0
0
8
0
0
% Q
% Arg:
16
8
0
16
0
8
0
0
0
0
8
0
0
8
0
% R
% Ser:
0
8
16
0
0
0
16
0
0
0
0
39
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
16
0
39
0
8
0
8
16
39
8
16
0
8
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
39
0
0
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _