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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL10
All Species:
25.15
Human Site:
Y352
Identified Species:
46.11
UniProt:
Q6JEL2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6JEL2
NP_689680.2
608
68942
Y352
G
G
F
D
S
V
D
Y
F
N
S
V
K
R
F
Chimpanzee
Pan troglodytes
XP_001167701
608
68899
Y352
G
G
F
D
S
V
D
Y
F
N
S
V
K
R
F
Rhesus Macaque
Macaca mulatta
XP_001093757
555
62750
V309
S
V
K
R
F
D
P
V
K
K
T
W
H
Q
V
Dog
Lupus familis
XP_537641
608
68948
Y352
G
G
F
D
S
V
D
Y
F
N
S
V
K
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V2
608
68958
Y352
G
G
F
D
S
V
D
Y
F
N
S
V
K
R
F
Rat
Rattus norvegicus
Q6JEL3
608
68944
Y352
G
G
F
D
S
V
D
Y
F
N
S
V
K
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
I445
G
W
C
S
G
D
A
I
S
S
V
E
R
Y
D
Chicken
Gallus gallus
XP_418155
584
66006
F338
G
T
A
F
L
K
G
F
V
Y
V
I
G
G
F
Frog
Xenopus laevis
Q6NRH0
564
63190
R315
L
P
S
I
T
R
K
R
R
Y
V
A
T
V
S
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
R315
L
P
N
I
A
R
K
R
R
Y
V
A
T
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
G376
D
L
L
Y
A
V
G
G
H
D
G
Q
S
Y
L
Honey Bee
Apis mellifera
XP_395435
661
75679
Y365
G
G
F
D
G
A
D
Y
F
N
S
C
R
C
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796178
830
95048
Y342
G
G
F
D
S
N
Q
Y
F
N
S
V
R
C
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
98.6
N.A.
98.8
98.8
N.A.
22.1
77.3
32.2
31.9
N.A.
35.3
47.2
N.A.
37.5
Protein Similarity:
100
99.8
90.3
99
N.A.
99.1
99.3
N.A.
39.6
85.1
50.3
50.1
N.A.
52.9
65.3
N.A.
51
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
6.6
13.3
0
0
N.A.
6.6
66.6
N.A.
73.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
20
26.6
6.6
6.6
N.A.
20
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
16
8
8
0
0
0
0
16
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
8
0
16
0
% C
% Asp:
8
0
0
54
0
16
47
0
0
8
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
54
8
8
0
0
8
54
0
0
0
0
0
62
% F
% Gly:
70
54
0
0
16
0
16
8
0
0
8
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
16
0
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
8
16
0
8
8
0
0
39
0
0
% K
% Leu:
16
8
8
0
8
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
54
0
0
0
0
0
% N
% Pro:
0
16
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
0
8
0
16
0
16
16
0
0
0
24
39
0
% R
% Ser:
8
0
8
8
47
0
0
0
8
8
54
0
8
0
8
% S
% Thr:
0
8
0
0
8
0
0
0
0
0
8
0
16
0
0
% T
% Val:
0
8
0
0
0
47
0
8
8
0
31
47
0
16
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
54
0
24
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _