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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL10
All Species:
22.12
Human Site:
Y599
Identified Species:
40.56
UniProt:
Q6JEL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6JEL2
NP_689680.2
608
68942
Y599
A
L
R
D
E
V
K
Y
S
A
S
T
S
T
L
Chimpanzee
Pan troglodytes
XP_001167701
608
68899
Y599
A
L
R
D
E
V
K
Y
S
A
S
T
S
T
L
Rhesus Macaque
Macaca mulatta
XP_001093757
555
62750
S547
L
R
D
E
V
K
Y
S
A
S
T
S
T
L
P
Dog
Lupus familis
XP_537641
608
68948
Y599
A
L
R
D
E
V
K
Y
S
A
S
T
S
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V2
608
68958
Y599
A
L
R
D
E
V
K
Y
S
A
S
T
S
T
L
Rat
Rattus norvegicus
Q6JEL3
608
68944
Y599
A
L
R
D
E
V
K
Y
S
A
S
T
S
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
M714
G
G
V
G
V
I
K
M
T
H
C
E
S
H
I
Chicken
Gallus gallus
XP_418155
584
66006
V576
V
V
P
G
L
C
N
V
G
D
Y
A
A
K
R
Frog
Xenopus laevis
Q6NRH0
564
63190
D555
S
M
A
T
Q
R
C
D
A
G
V
C
V
L
R
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
D555
S
M
A
T
Q
R
C
D
A
G
V
C
V
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
E615
T
E
N
Y
M
W
C
E
N
S
F
K
Q
P
N
Honey Bee
Apis mellifera
XP_395435
661
75679
Q629
P
Q
Q
D
Q
M
Q
Q
N
S
E
N
S
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796178
830
95048
T602
A
I
A
M
E
E
S
T
A
S
S
D
E
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
98.6
N.A.
98.8
98.8
N.A.
22.1
77.3
32.2
31.9
N.A.
35.3
47.2
N.A.
37.5
Protein Similarity:
100
99.8
90.3
99
N.A.
99.1
99.3
N.A.
39.6
85.1
50.3
50.1
N.A.
52.9
65.3
N.A.
51
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
13.3
0
0
0
N.A.
0
20
N.A.
20
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
33.3
13.3
26.6
26.6
N.A.
13.3
60
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
24
0
0
0
0
0
31
39
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
8
24
0
0
0
8
16
0
0
0
% C
% Asp:
0
0
8
47
0
0
0
16
0
8
0
8
0
0
0
% D
% Glu:
0
8
0
8
47
8
0
8
0
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
8
0
16
0
0
0
0
8
16
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
8
47
0
0
0
0
8
0
8
0
% K
% Leu:
8
39
0
0
8
0
0
0
0
0
0
0
0
24
47
% L
% Met:
0
16
0
8
8
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
16
0
0
8
0
0
8
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
0
8
8
0
24
0
8
8
0
0
0
0
8
8
0
% Q
% Arg:
0
8
39
0
0
16
0
0
0
0
0
0
0
8
24
% R
% Ser:
16
0
0
0
0
0
8
8
39
31
47
8
54
0
0
% S
% Thr:
8
0
0
16
0
0
0
8
8
0
8
39
8
39
0
% T
% Val:
8
8
8
0
16
39
0
8
0
0
16
0
16
0
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
39
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _