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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A25 All Species: 42.73
Human Site: S241 Identified Species: 72.31
UniProt: Q6KCM7 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6KCM7 NP_001006642.1 469 52663 S241 I R E G G A R S L W R G N G I
Chimpanzee Pan troglodytes XP_001153366 469 52663 S241 I R E G G A R S L W R G N G I
Rhesus Macaque Macaca mulatta XP_001088378 468 52373 S240 V L E G G I R S L W R G N G I
Dog Lupus familis XP_862510 469 52735 S241 I R E G G A K S L W R G N G I
Cat Felis silvestris
Mouse Mus musculus A2ASZ8 469 52602 S241 I R E G G A K S L W R G N G I
Rat Rattus norvegicus Q8K3P6 469 52677 S241 I R E G G A K S L W R G N G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505563 469 52720 S241 I R E G G A R S L W R G N G I
Chicken Gallus gallus XP_415513 469 52817 S241 I R E G G T R S L W R G N G I
Frog Xenopus laevis Q7ZYD5 514 56789 S286 I R E G G F R S L W R G N G I
Zebra Danio Brachydanio rerio A2CEQ0 469 52693 S241 I R E G G L R S L W R G N G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20799 588 66319 S303 H A E G G I K S F W R G N G I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609 A213 E H F T Y D T A K K F L T P K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798 R159 G N L P Q V I R V L P Y S A V
Baker's Yeast Sacchar. cerevisiae P48233 545 61252 N282 K N P N A D I N K I S S P L A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 63.7 97.8 N.A. 97.4 97 N.A. 96.3 93.5 76.2 85.7 N.A. N.A. N.A. 39.7 N.A.
Protein Similarity: 100 99.7 75.6 99.1 N.A. 98.7 98.7 N.A. 98.7 98 82.8 94 N.A. N.A. N.A. 58.1 N.A.
P-Site Identity: 100 100 80 93.3 N.A. 93.3 93.3 N.A. 100 93.3 93.3 93.3 N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: 100 100 86.6 100 N.A. 100 100 N.A. 100 93.3 93.3 93.3 N.A. N.A. N.A. 73.3 N.A.
Percent
Protein Identity: N.A. 28.3 N.A. 25.8 28.8 N.A.
Protein Similarity: N.A. 45.4 N.A. 42.8 47.5 N.A.
P-Site Identity: N.A. 0 N.A. 0 0 N.A.
P-Site Similarity: N.A. 6.6 N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 43 0 8 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 79 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 8 0 0 8 0 8 0 0 0 0 % F
% Gly: 8 0 0 79 79 0 0 0 0 0 0 79 0 79 0 % G
% His: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 65 0 0 0 0 15 15 0 0 8 0 0 0 0 79 % I
% Lys: 8 0 0 0 0 0 29 0 15 8 0 0 0 0 8 % K
% Leu: 0 8 8 0 0 8 0 0 72 8 0 8 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 15 0 8 0 0 0 8 0 0 0 0 79 0 0 % N
% Pro: 0 0 8 8 0 0 0 0 0 0 8 0 8 8 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 65 0 0 0 0 50 8 0 0 79 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 79 0 0 8 8 8 0 0 % S
% Thr: 0 0 0 8 0 8 8 0 0 0 0 0 8 0 0 % T
% Val: 8 0 0 0 0 8 0 0 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 79 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _